In vivo synthesis of connective tissues

Details In vivo synthesis of connective tissues In vivo synthesis of connective tissues

2004-09-14

2008-05-20

Rao, Manjunath (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S423000, C424S426000, C424S491000, C424S492000, C424S093700

Reexamination Certificate

active

07375077

ABSTRACT:
The in vivo synthesis of connective tissue by fibroblast or fibroblast precursor cells ensconced within a biocompatible scaffold is disclosed. The cells are preferably present in a biocompatible scaffold such as gelatin and placed between two other biocompatible scaffolds such as collagen sponges soaked with a collagenic amount of a member of the TGF-β family of proteins. This composition is then implanted in a host to produce cranial sutures, periodontal ligament or other fibrous tissue structures in vivo.

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