In-vivo spatially encoded magnetic resonance spectroscopy with s

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

G01R 3320

Patent

active

047712422

ABSTRACT:
A binomial pulse generator (32) selectively generates binomial radio frequency excitation pulses (60) which induce magnetic resonance only in selected hydrogen dipoles and suppresses resonance in others. An inversion pulse generator (34) generates a first inversion pulse (70) in the presence of a first magnetic field gradient (72) generated by a gradient control (22). The inversion pulse only inverts the magnetization of resonating nuclei in a first plane defined by the first magnetic field gradient. A second inversion pulse (74) applied in the presence of a second magnetic field gradient (76) inverts the magnetization of resonating nuclei in a second planar region defined by the second magnetic field gradient. A third inversion pulse (78) applied concurrently with a third magnetic field gradient (80) inverts the magnetization of resonating nuclei in a third planar region defined by the third magnetic field gradient. Only resonating nuclei in a volumetric element defined at the intersection of the first, second, and third planes are inverted all three times. The magnetization of other dipoles will have dephased differently from the dipoles in the volumetric element. In this manner, only the dipoles in the volumetric element contribute to a spin echo (82) which follows the third inversion pulse. Data acquired during the third spin echo may be spectrographically analyzed to determine the chemical composition within the volumetric element. Alternately, a phase encoding gradient (90) and a read gradient (92) may be applied as part of the sequence to provide the appropriate phase encoding to the acquired data such that the acquired data can be reconstructed into an image representation.

REFERENCES:
patent: 4480228 (1984-10-01), Bottomley
patent: 4506223 (1985-03-01), Bottomley et al.
patent: 4558277 (1985-12-01), Post et al.
patent: 4629988 (1986-12-01), Bottomley et al.
patent: 4678995 (1987-07-01), Avison et al.
"Solvent Suppresion in Fourier Transform Nuclear Magnetic Resonance", vol. 55, J. Mag. Res., pp. 283-300 (1983), Hore.
"Volume Selective Excitation, A Novel Approach to Topical NMR", Aue et al., vol. 50, J. Mag. Res., pp. 350-354 (1984).
"NMR Chemical Shift Imaging in Three Dimensions", Brown et al., Proc. Nat. Acad. Sci., vol. 79, pp. 3523-3526 (1982).
".sup.31 P Spectroscopic Zeugmatography of Phosphorus Metabolites", Bendel et al, vol. 38, J. Mag. Res., pp. 343-356 (1980).
"Spatially Resolved High Resolution Spectroscopy by Four Dimensional NMR", Maudsley et al., 51, J. Mag. Res. pp. 147-152 (1983).
"Towards Biochemical Imaging", Cox et al., vol. 40, J. Mag. Res., pp. 209-212 (1980).
"Depth-Resolved Surface-Coil Spectroscopy (Dress) for In-Vivo .sup.1 H, .sup.31 P, .sup.13 CNMR", Bottomley et al, 59, J. Mag. Res., pp. 338-342 (1982).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

In-vivo spatially encoded magnetic resonance spectroscopy with s does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with In-vivo spatially encoded magnetic resonance spectroscopy with s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and In-vivo spatially encoded magnetic resonance spectroscopy with s will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-808324

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.