In vivo port wine stain, burn and melanin depth...

Details In vivo port wine stain, burn and melanin depth... In vivo port wine stain, burn and melanin depth...

2008-01-29

2008-01-29

Hindenburg, Max F. (Department: 3736)

Surgery

Instruments

Light application

Reexamination Certificate

active

10359782

ABSTRACT:
A photoacoustic probe for port wine stain (PWS), burn and melanin depth measurements is comprised of optical fibers for laser light delivery and a piezoelectric element for acoustic detection. The probe induced and measured photoacoustic waves in acryl amide tissue phantoms and PWS skin in vivo. Acoustic waves were denoised using spline wavelet transforms, then deconvolved with the impulse response of the probe to yield initial subsurface pressure distributions in phantoms and skin. The waves were then analyzed for epidermal melanin concentration, using a photoacoustic melanin index (PAMI) related to the amount of laser energy absorbed by melanin. Propagation time of the photoacoustic wave was used to determine the depth of blood perfusion underlying necrotic, burned tissue. Thus, the photoacoustic probe can be used for determining PWS, burn and melanin depth for most patients receiving laser therapy.

REFERENCES:
patent: 5348002 (1994-09-01), Caro
patent: 5701902 (1997-12-01), Vari et al.
patent: 5792049 (1998-08-01), Eppstein et al.
patent: 5840023 (1998-11-01), Oraevsky et al.
patent: 6216540 (2001-04-01), Nelson et al.
patent: 6381488 (2002-04-01), Dickey et al.

Affiliated with

Also associated with

Rating

In vivo port wine stain, burn and melanin depth... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with In vivo port wine stain, burn and melanin depth..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and In vivo port wine stain, burn and melanin depth... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3935450