Surgery – Instruments – Light application
Reexamination Certificate
2008-01-29
2008-01-29
Hindenburg, Max F. (Department: 3736)
Surgery
Instruments
Light application
Reexamination Certificate
active
07322972
ABSTRACT:
A photoacoustic probe for port wine stain (PWS), burn and melanin depth measurements is comprised of optical fibers for laser light delivery and a piezoelectric element for acoustic detection. The probe induced and measured photoacoustic waves in acryl amide tissue phantoms and PWS skin in vivo. Acoustic waves were denoised using spline wavelet transforms, then deconvolved with the impulse response of the probe to yield initial subsurface pressure distributions in phantoms and skin. The waves were then analyzed for epidermal melanin concentration, using a photoacoustic melanin index (PAMI) related to the amount of laser energy absorbed by melanin. Propagation time of the photoacoustic wave was used to determine the depth of blood perfusion underlying necrotic, burned tissue. Thus, the photoacoustic probe can be used for determining PWS, burn and melanin depth for most patients receiving laser therapy.
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Jacques Steven L.
Nelson J. Stuart
Paltauf Guenther
Viator John A.
Hindenburg Max F.
Myers Dawes Andras & Sherman LLP
Smith Fangemonique
The Regents of the University of California
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