Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation
Patent
1997-04-08
1999-01-12
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Ophthalmic preparation
5147723, 514919, A61K 3174, A61K 4730
Patent
active
058583459
ABSTRACT:
Ophthalmic compositions containing biocompatible, bioadhesive polymerizable amphipathic mesophase materials useful for repairing retinal tissue tears or retinal detachments are disclosed. In one embodiment, the polymerizable materials, which comprise substituted fluoroalkyl or perfluoroalkyl monomers having anionic, cationic, and/or nonionic surface active functionality in the unsaturated fluorophobic ends, are polymerized in vivo to provide effective, long-lasting repair of torn, ruptured or detached retinal tissue. Ophthalmic applications of these materials are not limited to retinal repair.
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Charles Steven T.
Hammer Mark E.
Lang John C.
Lochhead Robert Y.
Mathias Lon J.
Alcon Laboratories Inc.
Azpuru Carlos
Ryan Patrick M.
Univ of Southern Mississippi
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