Surgery – Cardiac augmentation
Reexamination Certificate
2011-08-09
2011-08-09
Bertram, Eric D (Department: 3766)
Surgery
Cardiac augmentation
Reexamination Certificate
active
07993258
ABSTRACT:
A method and device featuring at least one component providing a potential to kinetic converted elastic, magnetic repulsion, or, an elastic and magnetic repulsion, pushing, pulling, or, pulling and pushing, type of radially outward expansive force or pressure to an inner, outer, intermediate, and, combination thereof, wall region of the left ventricle, for reducing intraluminal hydrostatic pressure of the left ventricle (LV filling pressure) during the ventricular diastolic stage of the cardiac cycle, thereby, improving diastolic function of the left ventricle of the heart in subjects having a condition of diastolic heart failure (DHF), while minimally disturbing systolic function of the heart. The expansive force or pressure is in a range of about 5-40 mm Hg, whereby, left ventricular end diastolic pressure (LVEDP) is reduced down to the normal range of about 6-12 mm Hg, during ventricular diastole of the heart.
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Vasan et al., “Diastolic Heart Failure—No Time to Relax”, New England Journal of Medicine, vol. 344, pp. 56-59, Jan. 4, 2001, 5 pages.
Opie, “The Heart Physiology, From Cell to Circulation,” 3rd Edition, Lippincott-Raven publishers, 1998, Chapter 12, Ventricular Function, pp. 343-389.
Mandinov et al., “Diastolic Heart Failure,” Cardiovascular Research, vol. 45, Issue 4, Mar. 2000, pp. 813-825.
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Morris-Thurgood et al., “Pacing in Heart Failure: Improved Ventricular Interaction in Diastole Rather than Systolic Re-Synchronization,” European Society of Cardiology, Europace, 2000, vol. 2, pp. 271-275.
Dubi Shay
Feld Yair
Bertram Eric D
Corassist Cardiovascular Ltd.
Nixon & Vanderhye P.C.
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