Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Patent
1992-02-20
1994-01-11
Stoll, Robert L.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
424 9, 530396, A61K 4902, A61K 4900
Patent
active
052778924
ABSTRACT:
Methods and reagents for the in vivo tagging of leukocytes, and in particular lymphocytes with a leukostimulatory agent and a linked medically useful metal ion, including a radioisotope, and subsequent detection of leukocyte or lymphocyte trafficking and sites of concentrated leukocytes or lymp
REFERENCES:
patent: 3812264 (1974-05-01), Nouel
patent: 4289747 (1981-09-01), Chu
patent: 4421735 (1983-12-01), Haber et al.
patent: 4424200 (1984-01-01), Crockford et al.
patent: 4479930 (1984-10-01), Hnatowich
patent: 4550086 (1985-10-01), Reinherz
patent: 4622420 (1986-11-01), Meares et al.
patent: 4634586 (1987-01-01), Goodwin et al.
patent: 4668503 (1987-05-01), Hnatowich
patent: 4670545 (1987-06-01), Fritzberg et al.
patent: 4724212 (1988-02-01), Epstein
patent: 4735210 (1988-04-01), Goldenberg
patent: 4861579 (1989-08-01), Meyer, Jr. et al.
patent: 4870015 (1989-09-01), Hoffman
patent: 4877868 (1989-10-01), Reno et al.
patent: 4917878 (1990-04-01), Thakur
patent: 4925648 (1990-05-01), Hansen et al.
patent: 4926869 (1990-05-01), Rubin et al.
patent: 4986979 (1991-01-01), Morgan, Jr. et al.
patent: 5002869 (1991-03-01), Schlossman et al.
patent: 5078985 (1992-01-01), Rhodes
patent: 5079343 (1992-01-01), Anderson et al.
patent: 5089604 (1992-02-01), Washino et al.
patent: 5120642 (1992-06-01), Schlossman
patent: 5128119 (1992-07-01), Griffiths
patent: 5143712 (1992-09-01), Brandley et al.
patent: 5200178 (1993-04-01), Strauss et al.
"The Labeling of High Affinity Sites of Antibodies with 99mTc," by Chang H. Paik et al., Int. J. Nucl. Med. Biol., vol. 12, No. 1, pp. 3-8 (1985).
"Technetium-99m Labeling of Murine Monoclonal Antibody Fragments," by Buck A. Rhodes et al., J. Nucl. Med., vol. 27, No. 5, pp. 685-693 (May 1986).
Astaldi, G., et al., "Antibodies to Phytohaemagglutinin" The Lancet, pp. 502-503 (Aug. 27, 1966).
Baidoo, Kwamena E., et al., ".sup.99m Tc Labeling of Proteins: Initial Evaluation of a Novel Diaminedithiol Bifunctional Chelating Agent," Cancer Res. (Supp), vol. 50, pp. 799s-803s (Feb. 1990).
Byrd, William J., et al., "Inhibition of Mitogenic Factor in Phytohaemagglutinin by an Antiserum," Nature, pp. 622-624 (Feb. 11, 1967).
El-Hag, Aly, et al., "Immunosuppression by Activated Human Neutrophils," Journal of Immun., vol. 139, No. 7, pp. 2406-2413 (Oct. 1, 1987).
Fritzberg, Alan R., et al., "Approaches to Radiolabeling of Antibodies for Diagnosis and Therapy of Cancer," Review, Pharmaceutical Research, vol. 5, No. 6, pp. 325-334 (1988).
Granowska, M., et al., "A Tc-99m Labelled Monoclonal Antibody, PR1A3, for Radioimmunoscintigraphy, RIS, of Colorectal Cancer," Proceedings of the 36th Annual Meeting, J. Nucl. Med., vol. 30, p. 748 (No. 80), (1989).
Greaves, M. F., et al., "Lymphocyte Activation," Clin. Exp. Immunol., vol. 10, pp. 537-554 (1972).
Hnatowich, D. J., "Antibody Radiolabelling, Problems and Promises," Nucl. Med. Biol., vol. 17, No. 1, pp. 49-55 (1990).
Hnatowich, D. J., "Recent Developments in the Radiolabeling of Antibodies with Iodine, Indium, and Technetium," Seminars in Nucl. Med., vol. XX, No. 1, pp. 80-91 (Jan. 1990).
Hoffman, Leslie, et al., "Synthesis of Mitogenic Phytohemagglutinin-L in Escherichia Coli," vol. 5, pp. 157-160 (Feb. 1987).
Houston, L. L., et al., "Specific In Vivo Localization of Monoclonal Antibodies Directed Against the Thy 1.1 Antigen.sup.1," Journal of Immun., vol. 125, No. 2, pp. 837-843 (Aug. 1980).
Krejcarek, Gary E., et al., "Covalent Attachment of Chelating Groups to Macromolecules," Biochem. & Biophy. Res. Comm., vol. 77, No. 2, pp. 581-585, (1977).
Lavender, J. P., et al., "Kinetics of indium-III labelled lymphocytes in normal subjects and patients with Hodgkin's disease," British Med. Journal. vol. 2, pp. 797-799 (1977).
Lever, Susan Z., et al., "Synthesis of a Novel Bifunctional Chelate Designed for Labeling Proteins with Technetium-99m," Tetrahedron Letters, vol. 29, No. 26, pp. 3219-3222 (1988).
Lindahl-Kiessling, K., "Mechanism of Phytohemagglutinin (PHA) Action," Experimental Cell Research, vol. 70, pp. 17-26 (1972).
Loutfi, Issa, et al., "In vivo imaging of rat lymphocytes with an indium 111-labeled anti-T cell monoclonal antibody: a comparison with indium 111-labelled lymphocytes," European Journal of Nuclear Medicine, vol. 16, pp. 69-76 (1990).
Pak, K. Y., et al., "A Rapid and Efficient Method for Labeling IgG Antibodies with Tc-99m and Comparison to Tc-99m FAB' Antibody Fragments," Scientific Papers, Proceedings of the 36th Annual Meeting, J. Nucl. Med., vol. 30, No. 5, p. 793 (No. 268), (1989).
Pettit, William A., et al., "Iodination and Acceptance Testing of Antibodies," Masson Publishing USA Inc., New York, pp. 99-109 (1982).
Rhodes, Buck A., "Direct Labeling of Proteins with .sup.99m Tc," Review, Nucl. Med., Biol., vol. 18, No. 7, pp. 667-676 (1991).
Rhodes, Buck A., et al., "Quality Control Test for Immunoreactivity of Radiolabeled Antibody," Research Report, BioTechniques, vol. 8, No. 1, pp. 70-74 (1990).
Rosenberg, Steve, "Lymphokine-Activated Killer Cells: A New Approach to Immunotherapy of Cancer," Guest Editorial, JNCI, vol. 75, No. 4 (Oct. 1985).
Schwarz, A., et al., "A Novel Approach to Tc-99m-Labeled Monoclonal Antibodies," Poster Sessions, Proceedings of 34th Ann. Mtg., J. Nucl. Med., vol. 28, No. 4, p. 721, (No. 695) (Apr. 1987).
Seaman, W. E., et al., "Selective Manipulation of the Immune Response In Vivo by Monoclonal Antibodies," Ann. Rev. Med., vol. 39, pp. 231-241 (1988).
Thakur, M. L., et al., "Indium-111-Labeled Autologous Leukocytes In Man," Journal of Nucl. Med., vol. 18, No. 10, pp. 1014-1021 (1977).
Thakur, M. L., "A Look At Radiolabeled Blood Cells," Nucl. Med. Biol., vol. 13, No. 2, pp. 147-158 (1986).
Thakur, M. L., et al., "Indium-111-labeled leukocytes for the localization of abscesses: preparation, analysis, tissue distribution, and comparison with gallium-67 citrate in dogs," Laboratory Methods, J. Lab. Clin. Med., vol. 89, pp. 217-228 (Jan. 1977).
Wagstaff, J., et al., "Human lymphocyte traffic assessed by indium-111 oxine labelling: clinical observations," Clin. Exp. Immunol., vol. 43, pp. 443-449 (1981).
Weber, T., "Kinetics of the Reaction of Kidney-Bean Leucoagglutinin with Human Lymphocytes," Experientia, vol. 29, pp. 863-865 (Jul. 1973).
Wensel, Theodore G., et al., "Bifunctional Chelating Agents for Binding Metal Ions to Proteins," S. W. Burchiel and B. A. Rhodes, Eds., Radioimmunoimaging and Radioimmunotherapy, pp. 185-196, (1983).
Wimer, Bruce M., "Potential Therapeutic Applications of PHA-L4 the Mitogenic Isolectin of Phytohemagglutinin," Mol. Biother., pp. 1-8 (1990).
Wimer, Bruce M., "Characteristics of PHA-L4, the mitogenic isolectin of phytohemagglutinin, as an ideal biologic response modifier," Review, Mol. Biother., vol. 2, pp. 4-17 (Mar. 1990).
Wimer, Bruce M., "Therapeutic activities of PHA-L4, the mitogenic isolectin of phytohemagglutinin," Review, Mol. Biother., vol. 2, pp. 74-90 (Jun. 1990).
Wimer, Bruce M., "The ideal biological response modifier," Mol. Biother., vol. 1, No. 6, pp. 311-317 (1989).
Advanced Immunology, Chapter 1 The Basis of Immunity.
Covert John M.
Duggan Donovan F.
Peacock Deborah A.
RhoMed Incorporated
Stoll Robert L.
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