In vivo and in vitro model of cutaneous photoaging

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Testing efficacy or toxicity of a compound or composition

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435 29, 4351723, 800 2, 935 59, A61K 4900, C12Q 102

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active

056480610

ABSTRACT:
A transgenic mouse capable of expressing human elastin promoter is provided. Mouse fibroblast cultures derived from this transgenic mouse are also provided. In addition methods of identifying compounds capable of inhibiting cutaneous photodamage with this transgenic mouse or fibroblast cultures derived from these mice are provided.

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