Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Patent
1998-08-11
1999-12-21
Weber, Jon P.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
435347, 435372, 435373, 435377, 435386, C12N 508
Patent
active
060048123
ABSTRACT:
The present invention provides an in vitro T-lymphopoiesis system in which a population of T-cells is produced from precursor cells expressing CD34. The T-lymphopoiesis system of the present invention produces a population of T-cells of which approximately 17-74% express CD2, approximately 1.5-34% express CD3, and approximately 16-61% express CD4, and approximately 0-15% express CD8. A method of producing such a population of T-cells in vitro, as well as various compositions including T-cells of the present invention, are also provided.
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Freedman Andrew
Scadden David T.
Beth Israel Medical Center, Inc.
Kerr Janet M.
Loren, Esq. Ralph A.
Weber Jon P.
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