Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-10-18
2005-10-18
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100, C435S068100
Reexamination Certificate
active
06955877
ABSTRACT:
A method for the selection of one or more desired polypeptides includes cell free expression of nucleic acid molecules immobilized on a solid support system to produce polypeptides. The solid support carrying system is for biospecific interaction with at least the desired polypeptide or a molecule attached thereto. The method also includes separation of the solid support carrying both the desired polypeptide and the nucleic acid encoding it. Finally, the method optionally includes recovery of the nucleic acid and/or the desired polypeptide, and molecular libraries for use in these methods.
REFERENCES:
patent: WO 98/54312 (1998-12-01), None
patent: WO 98/54312 (1998-12-01), None
patent: WO 99/02671 (1999-01-01), None
patent: WO 99/35293 (1999-07-01), None
Clackson, T and Wells, J A: Trends in Biotechnology, vol. 12, pp. 173-184 (1994).
Smith, G P and Petrenko, V A: American Chemical Society, vol. 97, pp. 391-410 (1997).
Mattheakis, L C et al: An in vitro polysome display system for identifying ligands from very large peptide libraries; Proceedings, The National Academy of Sciences of The USA, vol. 91, pp. 9022-9026 (Sep. 1994).
Hanes, J et al: Comparison ofEscherichia coliand rabbit reticulocyte ribosome display systems; Federation of European Biochemical Societies, Letters 450, pp. 105-110 (1999).
Roberts, R W and Szostak, J W: RNA-peptide fusion for thein vitroselection of peptides and proteins, Proceedings, The National Academy of Sciences of The USA, vol. 94, pp. 12297-12302 (Nov. 1997).
Lutz, J et al: Current Opinion in Biotechnology, vol. 9, pp. 534-548 (1998).
Roberts, R W: Current Opinion in Chemical Biology, vol. 3, pp. 268-273 (1999).
Nord, K et al: Protein Engineering, vol. 8, Issue 6, pp. 601-608 (1995).
Nord, K et al: Nature Biotechnology, vol. 15, pp. 772-777 (Aug. 1997).
Rüther, U: Nucleic Acids Research, vol. 10, No. 19, pp. 5765-5772 (1982).
Nygren, P-Å et al: Journal of Molecular Recognition, vol. 1, No. 2, pp. 69-74 (1988).
Carothers, A M et al: Biotechniques, vol. 7, No. 5, pp. 494-499 (1989).
Savolainen, P et al: Society for Molecular Biology and Evolution, vol. 17, No. 4, pp. 474-488 (2000).
Hopman, A H N et al: The Journal of Histochemistry and Cytochemistry, vol. 46, No. 6, pp. 771-777 (1998).
Larsson, M et al: Protein Expression and Purification, vol. 7, pp. 447-457 (1996).
Nilsson, B et al: Protein Engineering, vol. 1, No. 2, pp. 107-113 (1987).
Gunneriusson, E et al: Applied and Enviromental Microbiology, vol. 65, No. 9, pp. 4134-4140 (Sep. 1999).
Tawfick, D S and Griffiths, A D: Nature Biotechnology, vol. 16,pp. 652-656 (Jul., 1998).
Hanes, J and Plückthun, A:In vitroselection and evolution of functional proteins by using ribosome display; Proceedings, The National Academy of Sciences of the USA, vol. 94, pp. 4937-4942 (May, 1997).
Doi, N and Yanagawa, H: Federation of European Biochemical Societies, Letters 475, pp. 227-230 (1999).
Nord Olof
Nygren Per-Ake
Uhlen Mathias
Affibody AB
Calamita Heather G.
Garabedian Todd E.
Horlick Kenneth R.
Wiggin and Dana LLP
LandOfFree
In vitro selection and optional identification of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with In vitro selection and optional identification of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and In vitro selection and optional identification of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3435872