In vitro propagation of embryonic stem cells

Details In vitro propagation of embryonic stem cells In vitro propagation of embryonic stem cells

2007-03-06

2007-03-06

Woitach, Joseph (Department: 1632)

Multicellular living organisms and unmodified parts thereof and

Method of making a transgenic nonhuman animal

C800S018000, C800S025000

Reexamination Certificate

active

10121220

ABSTRACT:
The present invention relates to the use of leukemia inhibitory factor (LIF) in the isolation and propagation of embryonic stem cells in vitro.

REFERENCES:
patent: 4736866 (1988-04-01), Leder et al.
patent: 5166065 (1992-11-01), Williams et al.
patent: 5187077 (1993-02-01), Gearing et al.
patent: 5340740 (1994-08-01), Petitte et al.
patent: 5366888 (1994-11-01), Fry et al.
patent: 5843780 (1998-12-01), Thomson
patent: 6200806 (2001-03-01), Thomson
Martin (1981) “Isolation of a Pluripotent Cell Line from Early Mouse Embryos Cultured in Medium Conditioned by Teratocarcinoma Stem Cells” Proc. Natl. Acad. Sci. USA 78, 7634-7638.
Experimental approaches to mammalian embryonic development, edited by Robert & Pederson, Chapter 15, pp. 475-508 (1986).
Handyside, et al. (1987) “Towards the Isolation of Embryonal Stem Cell Lines from the Sheep” Roux's Arch. Dev. Biol. 196, 185-190.
Smith, et al. (1987) “Buffalo Rat Liver Cells Produce a Diffusible Activity which Inhibits the Differentiation of Murine Embryonal Carcinoma and Embryonic Stem Cells” Developmental Biology 121, 1-9.
Williams et al. (1988), Nature, 336: 684-687.
Health et al. (1988), J. Cell Sci. Suppl., 10: 257-266.
Doetschman, et al. (1988) “Establishment of Hamster Blastocyst-Derived Embryonic Stem (ES) Cells” Developmental Biology 127, 224-227.
Moreau et al. (1988), Nature, 336: 690-692.
Giugh et al. (1989), Reprod. Fert. Dev., vol. 1, pp. 281-288.
Nicholas, (1990) Development, 110:1341-1348.
Pease et al. (1990), Developmental Biology, 141: 344-352.
Pease et al. (1990), Experimental Cell Research, 190: 209-211.
Notarianni et al. (1991), J. Reprod., Fert., Suppl. 43: 255-260.
Saito et al., (1992) Roux's Arch Dev. Biol., vol. 201, pp. 134-141.
Sukoyan et al. (1992), Molecular Reproduction & Development, vol. 33, pp. 418,431.
Fry, R.C. (1992), Reprod. Fert. Dev., 4:449-458.
Yang et al. (1992), Theriogenology, vol. 38, pp. 315-335.
Fry et al. (1992), Biology of Reproduction, 46:470-474.
Scharfenstein, et al., (1996)“Identification, Isolation and Culture of Pluripotent Cells from the Porcine Inner Cell Mass” J. Anim. Breed. Genet. 113:427-436.
Wheeler, et al. (1994) Reprod. Fertil. Dev. 6:563-568.
Evans, et al. (1990) “Derivation and Preliminary Characterization of Pluripotent Cell Lines from Porcine and Bovine Blastocysts”, Theriogenology 33:125-128.
Piedrahita, et al. (1990) “Influence of Feeder Layer Type on the Efficiency of Isolation of Porcine Embryo Derived Cell Lines”, Theriogenology 34:865-877.
Piedrahita, et al. (1990) “On the Isolation of Embtryonic Stem Cells: Comparative Behavior or Murine, Porcine and Ovine Embryos”, Theriogenology 34:879-901.
Strojek, et al. (1990) “A Method for Cultivating Morphologenically Undifferentiated Embryonic Stem Cells from Porcine Blastocysts”, Theriogenology 33:901-913; and.
Bongso, et al. (1994) “Isolation and Culture of Inner Cell Mass Cells from Human Blastocysts”, Human Reprod. 9:2110.

Affiliated with

Also associated with

Rating

In vitro propagation of embryonic stem cells does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with In vitro propagation of embryonic stem cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and In vitro propagation of embryonic stem cells will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3760430