In vitro model for study of the pharmacodynamics of intracellula

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

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435 34, 435 4, 435 5, 435 732, 4352351, 4352402, 43524021, 43524022, 43524023, 4352531, 435863, 436 63, 436 74, C12Q 102, C12Q 104, C12Q 100, C12N 700

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active

057767211

ABSTRACT:
Adherent cell lines are grown on cover slips. The cover slips are placed in a culture media containing fluctuating concentrations of drugs for the purpose of testing simulated drug dosage regimens for use in the treatment of human infection. The cover slips are removed and the cells are harvested and processed for viable bacterial numbers of viral DNA over time.

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patent: 5447861 (1995-09-01), Collins et al.
patent: 5494660 (1996-02-01), Hunter et al.
patent: 5534413 (1996-07-01), Lo et al.

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