Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1998-02-10
2000-05-16
Housel, James C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530350, 530300, 530326, 530327, 530328, 530329, 5303881, 53038825, 5303893, C07K 14435, C07K 700
Patent
active
060639075
ABSTRACT:
Antibodies for detecting the presence of C-terminal hGPIIb fragment of the platelet receptor GPIIb-IIIa in a body fluid sample are disclosed.
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patent: 5763580 (1998-06-01), Ginsberg et al.
Loftus et al., "Molecular cloning and chemical synthesis of a region of a platelet glycoprotein IIb involved in adhesive function," Proceedings of the National Academy of Sciences USA, 84:7114-7118, Oct. 1987.
Shadle et al., "Platelet-Collagen Adhesion: Inhibition by a Monoclonal Antibody That Binds Glycoprotein IIb," The Journal of Cell Biology, 99:20566-2060, Dec. 1984.
Shattil et al., "Changes in the Platelet Membrane Glycoprotein IIb-IIIa Complex during Platelet Activation," The Journal of Biological Chemistry, 260:11107-11114, Sep. 1985.
Frelinger, III Andrew L.
Ginsberg Mark H.
Plow Edward F.
Fitting Thomas
Holmes Emily
Housel James C.
Nguyen Bao-Thuy L.
The Scripps Research Institute
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