In vitro-differentiated retinal ganglion cells and method...

Details In vitro-differentiated retinal ganglion cells and method... In vitro-differentiated retinal ganglion cells and method...

2007-12-04

2007-12-04

Li, Q. Janice (Department: 1633)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

C435S325000, C435S353000, C435S377000

Reexamination Certificate

active

11361342

ABSTRACT:
In vitro-differentiated retinal ganglion cells can be produced by exposing a mammalian retinal ganglion cell line to a protein kinase inhibitor. The differentiated retinal ganglion cells can be used to identify agents that protect retinal ganglion cells in vivo or in vitro from cell injury (including cell death) and agents that affect retinal ganglion cell ion channel activity.

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