Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1994-03-17
1998-11-03
Adams, Donald E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 71, 5303894, 4241391, 4241591, 4241881, C12Q 170
Patent
active
058306412
ABSTRACT:
The invention relates to a new class of retroviruses, designated by HIV-2, of which samples have been deposited to the ECACC under numbers 87.01.1001 and 87.01.1002 and to the NCIB under numbers 12.398 and 12.399.
It relates also to antigens capable to be obtained from this virus, particularly proteins p12, p16, p26 and gp140. These various antigens can be used for the diagnosis of the disease, especially by contacting these antigens with a serum of a patient submitted to the diagnosis.
It relates to immunogenic compositions containing more particularly the glycoprotein gp140. Finally it concerns nucleotidic sequences, which can be used especially as hybridization probes, derived from the RNA of HIV-2.
REFERENCES:
patent: 4629783 (1986-12-01), Cosand
patent: 4839288 (1989-06-01), Montagnier et al.
patent: 4877725 (1989-10-01), Neurath et al.
patent: 5051496 (1991-09-01), Alizon et al.
patent: 5066782 (1991-11-01), Montagnier et al.
patent: 5079342 (1992-01-01), Alizon et al.
patent: 5670309 (1997-09-01), Norrby et al.
Strongin, W., 1993, "Sensitivity, Specificity, and Predictive Value of Diagnostic Test: Definitions and Clinical Applications", in Laboratory Diagnosis of Viral Infections, Lennette, E., ed., Marcel Dekker Inc., New York, pp. 211-219.
Norrby et al. (1988, "Type-specific site-directed human immunodeficiency virus serology", in Vaccines 88, Cold Spring Harbor Laboratory, pp. 335-339).
Tedder et al. (1988, "Envelope cross-reactivity in western blot for HIV-1 and HIV-2 my not indicate dual infection", The Lancet 2:927-931.
Hunt et al., 1990, "Discrimination between HIV-1 and HIV-2-seropositive individuals using mouse monoclonal antibodies directed to HIV transmembrane proteins", AIDS Res. Human Retro. 6:883-898.
Laurence, J., "Update: HIV-1 gene nomenclature", AIDS Res. Hum. Retro. 4:vii-viii (1988).
Gallo et al., "HIV/HTLV gene nomenclature", Nature (London) 333:504 (1988).
Clavel et al., "Isolation of a new human retrovirus from West African patients with AIDS", Science 233:343-347 (1986).
L. Stryer, Biochemistry, pp. 761-763 (W. H. Freeman and Company, San Francsico, 1975).
Clavel et al., "Molecular Cloning and Polymorphism of the Human Immune Deficiency Virus Type 2", Nature, 324, 691-694 (1986).
Guyader et al., "Genome Organization and Transactivation of the Human Immunodeficiency Virus Type 2", Nature, 326, 662-669 (1987).
Wang et al., "Detection of Antibodies to Human T-lymphotropic Virus Type III by Using a Synthetic Peptide of 21 Amino Acid Residues Corresponding to a Highly Antigenic Segment of gp41 Envelope Protein", Proc. Natl. Acad. Sci., USA, 83, 6159-6163 (1986).
Chakrabarti et al., "Sequence of Simian Immunodeficiency Virus from Macaque and Its Relationship to Other Human and Simian Retroviruses", Nature, 328, 543-547 (1987).
Kanki et al., "Serologic Identification and Characterization of a Macaque T-lymphotropic Retrovirus Closely Related to HTLV-III," Science, 228, pp. 1199-1201 (1985).
Clavel et al., "Isolation of a New Human Retrovirus from West African Patients With AIDS," Science, 233, 343-346 (1986).
Clavel et al., "LAV Type II: A Second Retrovirus Associated With AIDS In West Africa," C.R. Acad. Sc. Paris, Serie III, 302, pp. 485-488 (1986).
Klatzmann et al., "T-lymphocyte T4 Molecule Behaves As The Receptor For Human Retrovirus LAV," Nature, 312, pp. 767-768 (1984).
Daniel et al., "Isolation of T-cell Tropic HTLV-III-like Retrovirus from Macaques," Science, 228, pp. 1201-1204 (1985).
Barin et al., "Serological Evidence For Virus Related To Simian T-lymphoctropic Retrovirus III in Residents of West Africa," The Lancet, pp. 1287-1389 (Dec. 21/28, 1985).
Sandstrom et al., "Antiviral Therapy In AIDS Clinical Pharmacological Properties and Therapeutic Experience to Date," Drugs, 34, pp. 372-390 (1987).
Mitsuya et al., "Protection of T Cells Against Infectivity and Cytopathic Effect of HTLV-III In Vitro," Retroviruses in Human Lymphoma/Leukemia, M. Miwa et al., eds., pp. 277-288 (Japan Science Press, Tokyo, 1985).
Alizon Marc
Clavel Fran.cedilla.ois
Guetard Denise
Guyader Mireille
Montagnier Luc
Adams Donald E.
Institut Pasteur
Parkin Jeffrey S.
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