In vitro chamber for human organ tissue samples

Details In vitro chamber for human organ tissue samples In vitro chamber for human organ tissue samples

1994-02-01

1995-09-19

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Apparatus

Bioreactor

435284, 435297, 435298, 435299, 435300, 220 238, 220420, 220422, 220427, 220426, 34192, 34195, 34197, 261125, 422205, C12M 100, C12M 106, C12M 118, C12M 300

Patent

active

054515246

ABSTRACT:
An in vitro chamber for sustaining organ tissue samples during optical study with, for example a microscope, has a tray assembly with a plurality of wells, each of which may be provided with a clampable sleeve or a vertically adjustable thimble such that an associated organ tissue sample contacts a nutrient medium contained in a reservoir. The tray assembly rests upon a heater assembly having a water-jet-driven magnetic stirrer magnetically coupled with a driven magnetic stirrer in the nutrient reservoir to maintain a substantially uniform temperature in both the heater assembly and the nutrient reservoir. A thermally insulating collar surrounding the tray assembly and the heater assembly maintains relative positions thereof. A transparent cover encloses the top of the tray assembly so that air borne exchanges with the wells and nutrient splashes are substantially contained.

REFERENCES:
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patent: 4090921 (1978-05-01), Sawamura et al.
patent: 4195131 (1980-03-01), Papas
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patent: 4673651 (1987-06-01), Rothenberg et al.
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patent: 4822741 (1989-04-01), Banes
patent: 4940853 (1990-07-01), Vandenburgh
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patent: 5153136 (1992-10-01), Vandenburgh
patent: 5238140 (1993-08-01), Maze
patent: 5366893 (1994-11-01), Stevens et al.
Fisher Catalog pp. 1534, 1538, 1539, 1546 Fisher Scientific, 1992.

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