Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1996-12-12
1998-05-12
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 5, 435 912, 435 911, 435 72, 536 231, 536 243, 536 2432, 536 2433, C12Q 168, C12Q 170, C12P 1934, C07H 2104
Patent
active
057503478
ABSTRACT:
The present invention concerns in situ polymerase chain reaction and provides methods and reagents for identifying cells containing at least one selected nucleic acid sequence which may be derived from the human immunodeficiency virus.
REFERENCES:
patent: 5008182 (1991-04-01), Sninsky et al.
patent: 5192503 (1993-03-01), McGrath et al.
patent: 5273905 (1993-12-01), Muller et al.
patent: 5382511 (1995-01-01), Stapleton
Clouse et al. Monokine Regulation of Human Immunodeficiency Virus-1 Expression In a Chronically Infected Human T. Cell Clone J. Immunol. 1989 142:431.
Folks et al. Cytokine-Induced Expression of HIV-1 in a Chronically Infected Promonocyte Cell Line Science 1987 238:800.
Haase et al. Amplification and detection of lentiviral DNA inside cells Proc. Natl. Sci. 1990 87:4971.
Harper et al. Detection of lymphocytes expressing human T-lymphotropic virus type III in lymph nodes and peripheral blood from infected individuals by in situ hybridization Proc. Natl. Acad. Sci. 1986 83:772.
Schnittman et al. The Reservoir for HIV-1 in Human Peripheral Blood is a T Cell That Maintains Expression of CD4 Science 1989 245:305.
Schnittman et al. Increasing Viral Burden in CD4+ T Cells from Patients with HIV Infection Reflects Rapidly Progressive Immunosuppression and Clinical Disease Ann. Int. Med. 1990 113:438.
Spector et al. Human Immunodeficiency Virus DNA is Present in a High Percentage of CD4+ Lymphocytes of Seropositive Individuals J. Infect. Dis. 1991 164:470.
Sundstrom et al. Establishment and Characterization of a Human Histocytic Lymphoma Cell Line Int. J. Cancer 1976 17:565.
Bagasra, O. Amplifications a Forum for PCR Users Polymerase Chain Reaction in situ Mar. 1990 Issue 4 pp. 20-21.
Embretson et al. PCR Amplification of Viral DNA and Viral Host Cell mRNAs in Situ The Polymerase Chain Reaction 1994 Birkhauser Boston.
Bagasra et al. Detection of Human Immunodeficiency Virus Type 1 Provirus in Mononuclear Cells by IN Situ Polymerase Chain Reaction New Eng. J. Med. 1992 326:1385.
Bagasra et al. anti-Human Immunodeficiency Virus Type 1 Activity of Sulfated Monosaccharides J. Infect. Dis. 1991 164:1082.
Nagai et al. Detection of Papillmavirus Nucleic Acids in Genital Precancers with the In Situ Hybridization Technique Internat'l Jour of Gynec. Path. 1987 6:366-379.
Godard C. Improved Method for Detection of Cellular Transcripts by in situ Hybridization Histochemistry 1983 77:123-131.
Nuovo et al. Importance of Different Variable for Enhancing in situ Detection of PCR-amplified DNA PCR Methods and Applications 1993 2:305-312.
Nuovo et al. Detection of Human Papillomavirus DNA in Formalin-fixed Tissues by In Situ Hybridization After Amplification by Polymerase Chain Reaction Journal of Pathology 1991 39:847-854.
Nuovo et al. Improved Technique for the In Situ Detection of DNA After Polymerase Chain Reaction Amplification American Journal of Pathology 1991 139:1239-1244.
Bagasra Omar
Pomerantz Roger J.
Rees Dianne
Thomas Jefferson University
Zitomer Stephanie W.
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