In situ gelling self-reactive materials for embolization

Details In situ gelling self-reactive materials for embolization In situ gelling self-reactive materials for embolization

2004-04-26

2011-11-01

Fubara, Blessing (Department: 1613)

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

C424S009400, C424S078310, C424S078370

Reexamination Certificate

active

08048407

ABSTRACT:
A method and composition for treating arteriovenous malformations (AVMs), or abnormal vasculature in the body are provided. The method comprises introducing into the region of an AVM a composition comprising a nucleophilic component, such as a thiol, and a component containing a conjugated unsaturated bond, such as an acrylate through a catheter, whereby the composition crosslinks within the body to block or occlude the AVM.

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