Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-02-16
2010-11-09
Cheu, Jacob (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S006120
Reexamination Certificate
active
07829291
ABSTRACT:
The present invention provides for the simultaneous assessment of a plurality of tissue regions or microregions, the benefit being homogeneity of the sampling, both in terms of tissue content and timing. Discrete regions of a tissue sample, such as those demarcated by microwells formed within the tissue itself or tissue plugs removed from the tissue in a spatially referenced fashion, can be treated with one or more physical or chemical treatments to liberate target molecules of interest. Subsequent analysis of said target molecules by, e.g., mass spectroscopy, permits identification of a variety of biological parameters, including those associated with disease or therapy.
REFERENCES:
patent: 4932412 (1990-06-01), Goldenberg
patent: 6677503 (2004-01-01), Bidney et al.
patent: 6707038 (2004-03-01), Ellson et al.
patent: 6809315 (2004-10-01), Ellson et al.
patent: 7534338 (2009-05-01), Hafeman et al.
patent: 2003/0186287 (2003-10-01), Lin et al.
patent: 2007/0082356 (2007-04-01), Strom et al.
patent: WO 0126460 (2001-04-01), None
patent: WO 03034024 (2003-04-01), None
Yanagisawa et al., “Proteomic patterns of tumour subsets in non-small-cell lung cancer,”The Lancet, 362:433-439, 2003.
Cheu Jacob
Fulbright & Jaworski L.L.P.
Vanderbilt University
LandOfFree
In situ analysis of tissues does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with In situ analysis of tissues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and In situ analysis of tissues will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4216010