Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Light application
Patent
1996-04-16
1998-06-16
Bahr, Jennifer
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Light application
607 88, 128642, 606 14, A61N 700
Patent
active
057662347
ABSTRACT:
A plurality of embodiments for a flexible probe used to provide photodynamic therapy (PDT) and to effect other medical procedures at an internal treatment site inside a patient's body. Each of the embodiments of the flexible probe (100, 108, 130, 158, 182, 190, 220, 280, 370, 390, 440, 460, 520) includes a flexible substrate (102, 184, 196, 222, 250, 282, 412, 462, 482, 502, 522) on which are disposed conductive traces (414, 466, 468, 488, 490, 504, 506, 524, 526) electrically connected to leads through which electrical current and signals are conveyed. A plurality of light sources (104, 192, 256, 286, 418, 436, 470, 492, 508, 542) or other micro-electronic circuits are connected to the conductive traces and mounted on the flexible substrate. Each of the embodiments of the flexible probes is enclosed within a transparent, biocompatible polymer envelope (106, 110, 464, 522). Due to the characteristic elastic properties of the flexible substrate, the flexible probe can readily be bent, folded, or rolled while being disposed at the internal treatment site. Thus, for example, a curved surgical needle (650) can be used to implant a flexible probe at the treatment site by drawing the flexible probe through tissue along a curved path to a desired position; one or more disk-shaped buttons (660, 670) that are attached to the ends of the flexible probe can be used to secure the flexible probe so that it does not move from the desired position.
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Barth et al., "Monolithic Silicon Fabrication Technology for Flexible Circuit and Sensor Arrays," pp. 83-86.
Schmidt et al., "Light-Emitting Diodes as a Light Source for Intraoperative Photodynamic Therapy," Neurosurgery, vol. 38, No. 3, Mar. 1996, pp. 552-557.
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Chen James C.
Wiscombe Brent
Anderson Ronald M.
Bahr Jennifer
Light Sciences Limited Partnership
Yarnell Bryan K.
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