Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1995-06-05
2000-12-05
Hauda, Karen M.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 932, 435375, 435325, 435366, 514 44, A61K 4800, C12N 1563, C12N 510, C12N 1509
Patent
active
061563056
ABSTRACT:
A method to prevent or treat cancer in a patient comprising: administering a first set of tumor cells; where at least some of the first tumor cells have at least one tumor antigen corresponding to antigen of the patient's tumor cells; where the tumor cells are contained in an implantable chamber; the chamber defined by a wall including a porous boundary between the patient's immune cells and the contained cells and pervious to subcellular antigenic material; where the boundary prevents contact between patient immune cells and the contained tumor cells, and where the boundary permits subcellular antigenic materials to exit the chamber; and rendering a second set of tumor cells nontumorigenic; where at least some of the second tumor cells have at least one tumor antigen corresponding to antigen of the patient's tumor cells; administering the second tumor cells to the patient without containing them in a chamber.
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Brauker James H.
Geller Robin Lee
Johnston William D.
Levon Steven A.
Maryanov David A.
Baxter International Inc.
Hauda Karen M.
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