Implantation device for use in vivo stimulation and collection o

Details Implantation device for use in vivo stimulation and collection o Implantation device for use in vivo stimulation and collection o

1982-08-11

1985-03-19

Pellegrino, Stephen C.

Surgery

Truss

Pad

128 1R, A61B 1000

Patent

active

045052778

ABSTRACT:
An apparatus for in vivo stimulation and collection of monocytes from peritoneum of vertebrate is disclosed. The apparatus is implanted between the skin and the peritoneum. This device stimulates the production and growth of monocytes and at the same time attracts the monocytes into the apparatus. The apparatus comprises a container which has a plurality of membrane-covered holes for monocyte entry. There is an inlet and outlet conduit which is attached to opposing sides of the container to allow flushing. The conduits are equipped with a lock tip coupler for connection when the flushing operation is not taking place.

REFERENCES:
patent: 3313289 (1967-04-01), Kapral
patent: 4364394 (1982-12-01), Wilkinson
Veale et al., "Differential Ability of Colonial Types of Neisseria Gonorroeae to Produce Infection and an Inflammatory Response in Subcutaneous Perforated Chambers in Guinea-Pigs and Rabbits", J. Med. Microbiol., vol. 8, 1975, pp. 325-334.

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