Implantable suture sleeve modified to reduce tissue ingrowth

Details Implantable suture sleeve modified to reduce tissue ingrowth Implantable suture sleeve modified to reduce tissue ingrowth

1996-06-14

1998-01-20

Bahr, Jennifer

Surgery

Radioactive substance applied to body for therapy

Radioactive substance placed within body

604174, 607116, A61N 500

Patent

active

057096449

ABSTRACT:
An implantable suture sleeve for use with an implantable lead with a pacemaker/cardioverter/defibrillator lead. Since irradiation from a radioisotope source is capable of inhibiting the growth of hyperproliferating cells as compared with normal cells, a radioisotope material which is incorporated into the lead can be used to decrease the rate of fibrotic growth. The radioisotope may be located inside the suture sleeve, alloyed into or coated onto the metal from which a wire or coil within the suture sleeve is made, or molded into the rubber of the suture sleeve. Beta emitting radioisotopes having a half-life between 1 and 100 days would be best suited as the radioactive material due to their comparatively short range of action within human tissue, and because of their comparatively short half-life.

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"Less-Invasive Techniques may Dominate Cardiovascular Therapy", Cardiovascular Device Update, Apr. 1996, pp. 1-16.

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