Implantable substrate coated with a macromer having free...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S426000, C424S484000, C424S486000, C424S078080, C424S078370, C424S093100, C424S093700, C435S178000, C435S180000, C435S182000, C435S395000, C514S002600, C530S812000, C530S813000, C530S815000, C530S817000

Reexamination Certificate

active

07153519

ABSTRACT:
Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules.

REFERENCES:
patent: 3960150 (1976-06-01), Hussain et al.
patent: 3981303 (1976-09-01), Higuchi et al.
patent: 3986510 (1976-10-01), Higuchi et al.
patent: 3993071 (1976-11-01), Higuchi et al.
patent: 4076800 (1978-02-01), Marsh et al.
patent: 4193845 (1980-03-01), Kaetsu et al.
patent: 4194066 (1980-03-01), Kaetsu et al.
patent: 4195129 (1980-03-01), Fukui et al.
patent: 4226938 (1980-10-01), Yoshida et al.
patent: 4272617 (1981-06-01), Kaetsu et al.
patent: 4283325 (1981-08-01), Berthet et al.
patent: 4295762 (1981-10-01), Slovinsky
patent: 4298002 (1981-11-01), Ronel et al.
patent: 4321117 (1982-03-01), Kaetsu et al.
patent: 4329332 (1982-05-01), Couvreur et al.
patent: 4352883 (1982-10-01), Lim
patent: 4359483 (1982-11-01), Kaetsu et al.
patent: 4376059 (1983-03-01), Davis et al.
patent: 4391909 (1983-07-01), Lim
patent: 4409331 (1983-10-01), Lim
patent: 4411754 (1983-10-01), Kaetsu et al.
patent: 4434150 (1984-02-01), Azad et al.
patent: 4450150 (1984-05-01), Sidman
patent: 4511478 (1985-04-01), Nowinski et al.
patent: 4526938 (1985-07-01), Churchill et al.
patent: 4563489 (1986-01-01), Urist
patent: 4590068 (1986-05-01), Berthet et al.
patent: 4605622 (1986-08-01), Hasegawa et al.
patent: 4637931 (1987-01-01), Schmitz
patent: 4647536 (1987-03-01), Mosbach et al.
patent: 4652443 (1987-03-01), Yoshida et al.
patent: 4663286 (1987-05-01), Tsang et al.
patent: 4689293 (1987-08-01), Goosen et al.
patent: 4744933 (1988-05-01), Rha et al.
patent: 4745160 (1988-05-01), Churchill et al.
patent: 4749620 (1988-06-01), Rha et al.
patent: 4774178 (1988-09-01), Egerer et al.
patent: 4791061 (1988-12-01), Sumino et al.
patent: 4804691 (1989-02-01), English et al.
patent: 4806355 (1989-02-01), Goosen et al.
patent: 4822535 (1989-04-01), Ekman et al.
patent: 4826945 (1989-05-01), Cohn et al.
patent: 4888413 (1989-12-01), Domb
patent: 4889722 (1989-12-01), Sheffield et al.
patent: 4913903 (1990-04-01), Sudmann et al.
patent: 4916193 (1990-04-01), Tang et al.
patent: 4925677 (1990-05-01), Feijen
patent: 4931279 (1990-06-01), Bawa et al.
patent: 4938763 (1990-07-01), Dunn et al.
patent: 4942035 (1990-07-01), Churchill et al.
patent: 4950596 (1990-08-01), Cheng et al.
patent: 4957744 (1990-09-01), della Valle et al.
patent: 5037656 (1991-08-01), Pitt et al.
patent: 5047020 (1991-09-01), Hsu
patent: 5149416 (1992-09-01), Osterhoudt et al.
patent: 5153002 (1992-10-01), McMullen
patent: 5160745 (1992-11-01), DeLuca et al.
patent: 5183690 (1993-02-01), Carr et al.
patent: 5185408 (1993-02-01), Tang et al.
patent: 5219564 (1993-06-01), Zalipsky et al.
patent: 5268182 (1993-12-01), Brinker et al.
patent: 5271961 (1993-12-01), Mathiowitz et al.
patent: 5278201 (1994-01-01), Dunn et al.
patent: 5278202 (1994-01-01), Dunn et al.
patent: 5286495 (1994-02-01), Batich et al.
patent: 5288500 (1994-02-01), Ibsen
patent: 5334640 (1994-08-01), Desai et al.
patent: 5410016 (1995-04-01), Hubbell et al.
patent: 5432210 (1995-07-01), Bogan, Jr.
patent: 5529914 (1996-06-01), Hubbell et al.
patent: 5573934 (1996-11-01), Hubbell et al.
patent: 5834274 (1998-11-01), Hubbell et al.
patent: 5837747 (1998-11-01), Soon-Shiong et al.
patent: 5843743 (1998-12-01), Hubbell et al.
patent: 0 195 304 (1993-10-01), None
patent: 1-324743 (1991-08-01), None
patent: WO 91/10425 (1991-07-01), None
patent: WO 93/09176 (1993-05-01), None
patent: WO 93/17669 (1993-09-01), None
patent: WO 93/21266 (1993-10-01), None
Altman, et al., “Long-term plasma glucose normalization in experimental diabetic rats with microencapsulated implants of benign human insulinomas,”Diabetes35:625-33 (1986).
Amudeswari, et al., “Short-term biocompatability studies of hydrogel-grafted collagen copolymers,”J. Biomed. Materials Res. 20:1103-09 (1986).
Andrade, et al., “Protein Adsorption and Materials Biocompatibility: A Tutorial Review and Suggested Hypothesis,”Advances in Polymer Science, published by Springer-Verlag Berlin Heidelberg, pp. 1-63 (1986).
Buck, “Cell Surface Receptors for Extracellular Matrix Molecules,”Ann. Rev. Cell Bio. 3:179-205 (1987).
Chesneau, et al., “Polymerization induito sous Irradiation Lager Visible,”J. Bio. Ang. Chemie. 135:41-64 (1985).
Chiang, et al., “Preparation and properties of UV-autocurable BTDA-based polyester multiacrylates. I. effects of acrylic functionality and polyl molecular weight,”J. App. Pol. Sci. 41:2971-85 (1990).
Chun, et al., “Studies on microbial transformations XIX, use of immobilized cells ofStreptomycas roseochromogenesfor the 16 a-hydroxyolation of dehydroepiandrosterone,”J. Gen. App. Microbiol. 27:505-09 (1981).
Cohn, et al., “Biodegradable PEO/PLA block copolymer,”J. Biomed. Materials Research22:993-1009 (1988).
Coleman, et al., “Blood-materials interactions: The minimum interfacial free energy and the optimum polar/apolar ratio hypothesis,”J. Biomed. Material Res. 16:381-398 (1982).
Crooks, et al., “Microencapsulation of mammalian cells in a HEMA-MMA copolymer: effects on capsule morphology and permeability,”J. of Biomedical Materials Res. 24:1241-62 (1990).
Darquy, et al., “Immunoisolation of pancreatic a cells by microencapsulation—anin vitrostudy,”Diabetologia28:776-80 (1985).
Dennison, Ph.D. Thesis, Massachusetts Institute of Technology (1986).
Desai, et al., “Solution technique to incorporate polyethylene oxide and other water-soluble polymers into surfaces of polymeric biomaterials,”Biomaterials12:144-53 (1991).
Desai, et al., “Surface modifications of polymeric biomaterials for reduced thrombogenicity,”Polymeric Materials Science and Engineering Proceedings of the ACS Division of Polymeric Materials Science and Engineering62:731-35 (1990).
Desai, et al., “Surface physical interpenetrating networks of poly(ethylene terephthalate) and poly(ethylene oxide) with biomedical applications,”Macromolecules25:226-32 (1992).
Desai, et al., “The short-term blood biocompatibility of poly(hydroxyethyl methacrylate-co-methyl methacrylate) in anin vitroflow system measured by the digital vieomicroscopy,”J. Biomaterial Sci. Polymer Ed. 1(2):123-46 (1989).
Diamond, et al., “Synergistic effects of interceed (Tc7) and heparin in reducing adhesion formation in the rabbit uterine horn model,”Fertility and Sterility55(2):389-94 (1991).
Domb, et al., “Poly(anhydrides). 3. poly(anhydrides) based on aliphatic aromatic diacids,”J. Macromolecules22:3200-04 (1989).
Doody, et al., “Recombinant tissue plasminogen activity reduces adhesion formation in a rabbit uterine horn model,”Fertility and Sterility51(3):509-12.
Dunn, et al., “Synergistic effect of intraperitoneally administered calcium channel blockade and recombinant tissueplasminogen activator to prevent adhesion formation in an animal model,”Am. J. Obstetn. and Gynecol. 164(5):1327-.30 (1991).
Dupuy, et al., “In SituPolymerization of a Microencapsulating Medium Round Living Cells,”J. of Biomedical Materials Res. 22:1061-70 (1988).
Dupuy, et al., “Microencapsulation of isolated pituitary cells by polyacrylamide microlatex coagulation on agarose beads,”Biomaterials12:493-495 (1991).
Eaton, “Dye sensitized photopolymerization,”Advances in Photochemistry, 13:427-81 (John Wiley & Sons, Inc. 1986).
Epaillard, et al., “Plasma Induced Polymerization,”J. Applied Pol

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Implantable substrate coated with a macromer having free... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Implantable substrate coated with a macromer having free..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Implantable substrate coated with a macromer having free... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3698411

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.