Implantable refillable and ported controlled release drug...

Details Implantable refillable and ported controlled release drug... Implantable refillable and ported controlled release drug...

2005-02-08

2005-02-08

Hayes, Michael J. (Department: 3763)

Surgery

Controlled release therapeutic device or system

Implanted dynamic device or system

C604S288030

Reexamination Certificate

active

06852106

ABSTRACT:
An implantable, refillable, rate controlled drug delivery device is disclosed that includes a base structure having at least a first opening and a second opening, the base structure defining a chamber, a septum covering the first opening and configured to substantially prevent leakage from the first opening to an exterior of the device, a drug delivery tube comprising a first and second distal end, wherein the first distal end of the tube communicates with the chamber through the second opening, and at least one rate-limiting permeable membrane disposed across a passage between the base structure and the second distal end of the drug delivery tube, which membrane passively regulates drug delivery. The drug delivery device is used to provide controlled drug delivery to an internal portion of the body and is advantageously leak-proof and does not rely on a pressure differential to drive the drug from the device.

REFERENCES:
patent: 3640269 (1972-02-01), Delgado
patent: 4784646 (1988-11-01), Feingold
patent: 5085644 (1992-02-01), Watson et al.
patent: 5185003 (1993-02-01), Brethauer
patent: 5205820 (1993-04-01), Kriesel
patent: 5647855 (1997-07-01), Trooskin
patent: 5695490 (1997-12-01), Flaherty et al.
patent: 5836935 (1998-11-01), Ashton et al.

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