Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Having plural layers
Reexamination Certificate
2011-08-09
2011-08-09
Gherbi, Suzette J (Department: 3738)
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Having plural layers
C427S002100
Reexamination Certificate
active
07993390
ABSTRACT:
Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.
REFERENCES:
patent: 4036227 (1977-07-01), Zaffaroni et al.
patent: 4054139 (1977-10-01), Crossley
patent: 4240163 (1980-12-01), Galin
patent: 4472327 (1984-09-01), Neefe
patent: 4603152 (1986-07-01), Laurin et al.
patent: 4723950 (1988-02-01), Lee
patent: 4731080 (1988-03-01), Galin
patent: 4853978 (1989-08-01), Stockum
patent: 4902503 (1990-02-01), Umemura et al.
patent: 4923450 (1990-05-01), Maeda et al.
patent: 4933178 (1990-06-01), Capelli
patent: 4946899 (1990-08-01), Kennedy et al.
patent: 4978391 (1990-12-01), Jones
patent: 5080892 (1992-01-01), Yamamori et al.
patent: 5091205 (1992-02-01), Fan
patent: 5091442 (1992-02-01), Milner
patent: 5098379 (1992-03-01), Conway et al.
patent: 5102401 (1992-04-01), Lambert et al.
patent: 5102402 (1992-04-01), Dror et al.
patent: 5130159 (1992-07-01), Shlenker et al.
patent: 5135516 (1992-08-01), Sahatjian et al.
patent: 5137671 (1992-08-01), Conway et al.
patent: 5165952 (1992-11-01), Solomon et al.
patent: 5171318 (1992-12-01), Gibson et al.
patent: 5176665 (1993-01-01), Watanabe et al.
patent: 5178870 (1993-01-01), Schaeken et al.
patent: 5217493 (1993-06-01), Raad et al.
patent: 5261896 (1993-11-01), Conway et al.
patent: 5272012 (1993-12-01), Opolski
patent: 5279594 (1994-01-01), Jackson
patent: 5304121 (1994-04-01), Sahatjian
patent: 5328698 (1994-07-01), Onwumere et al.
patent: 5328954 (1994-07-01), Sarangapani
patent: 5344411 (1994-09-01), Domb et al.
patent: 5360415 (1994-11-01), Yabushita et al.
patent: 5362754 (1994-11-01), Raad et al.
patent: 5366505 (1994-11-01), Farber
patent: 5370681 (1994-12-01), Herweck et al.
patent: 5389314 (1995-02-01), Wang
patent: 5409012 (1995-04-01), Sahatjian
patent: 5462644 (1995-10-01), Woodson
patent: 5468787 (1995-11-01), Braden et al.
patent: 5512055 (1996-04-01), Domb et al.
patent: 5569463 (1996-10-01), Helmus et al.
patent: 5599298 (1997-02-01), Sahatjian
patent: 5607683 (1997-03-01), Capelli
patent: 5611354 (1997-03-01), Alleyne
patent: 5616119 (1997-04-01), Davis
patent: 5624704 (1997-04-01), Darouiche et al.
patent: 5643207 (1997-07-01), Rise
patent: 5679399 (1997-10-01), Shlenker et al.
patent: 5693034 (1997-12-01), Buscemi et al.
patent: 5707366 (1998-01-01), Solomon et al.
patent: 5716406 (1998-02-01), Farber
patent: 5741331 (1998-04-01), Pinchuk
patent: 5772640 (1998-06-01), Modak et al.
patent: 5853745 (1998-12-01), Darouiche
patent: 5902283 (1999-05-01), Darouiche et al.
patent: 6048844 (2000-04-01), Falk et al.
patent: 6083208 (2000-07-01), Modak et al.
patent: 6096070 (2000-08-01), Ragheb et al.
patent: 6106505 (2000-08-01), Modak et al.
patent: 6224579 (2001-05-01), Modak et al.
patent: 6261271 (2001-07-01), Solomon et al.
patent: 6468649 (2002-10-01), Zhong
patent: 6475434 (2002-11-01), Darouiche
patent: 6482830 (2002-11-01), Redkar et al.
patent: 6545097 (2003-04-01), Pinchuk et al.
patent: 6641831 (2003-11-01), Schierholz
patent: 6706024 (2004-03-01), Modak et al.
patent: 6719991 (2004-04-01), Darouiche et al.
patent: 6887270 (2005-05-01), Miller et al.
patent: 6921390 (2005-07-01), Bucay-Couto et al.
patent: 6929705 (2005-08-01), Myers et al.
patent: 2001/0010016 (2001-07-01), Modak et al.
patent: 2001/0022988 (2001-09-01), Schwarz et al.
patent: 2002/0031601 (2002-03-01), Darouiche et al.
patent: 2002/0107330 (2002-08-01), Pinchuk et al.
patent: 2003/0018306 (2003-01-01), Bucay-Couto et al.
patent: 2003/0024534 (2003-02-01), Silvestri et al.
patent: 2003/0078242 (2003-04-01), Raad et al.
patent: 2003/0153983 (2003-08-01), Miller et al.
patent: 2003/0199993 (2003-10-01), Gellman et al.
patent: 2003/0203991 (2003-10-01), Schottman et al.
patent: 2003/0224033 (2003-12-01), Li et al.
patent: 2004/0022824 (2004-02-01), Li et al.
patent: 2004/0166094 (2004-08-01), Darouiche et al.
patent: 2004/0166102 (2004-08-01), Darouiche et al.
patent: 2004/0208908 (2004-10-01), Modak et al.
patent: 2004/0249441 (2004-12-01), Miller et al.
patent: 2005/0161859 (2005-07-01), Miller et al.
patent: 2005/0255230 (2005-11-01), Clerc et al.
patent: 2005/0271698 (2005-12-01), Bucay-Couto et al.
patent: 2006/0264912 (2006-11-01), McIntyre et al.
patent: 3347660 (1985-07-01), None
patent: 0 328 421 (1989-08-01), None
patent: 0328421 (1989-08-01), None
patent: 0 379 271 (1990-07-01), None
patent: 0379271 (1990-07-01), None
patent: 0970711 (2000-01-01), None
patent: 01-121065 (1889-05-01), None
patent: 01-178540 (1989-07-01), None
patent: 04-500469 (1992-01-01), None
patent: 05-21960 (1993-03-01), None
patent: 08-117326 (1996-05-01), None
patent: 08-199002 (1996-08-01), None
patent: 10-024101 (1998-01-01), None
patent: 11-500330 (1999-01-01), None
patent: 2000-507842 (2000-06-01), None
patent: 90/02573 (1990-03-01), None
patent: 93/10847 (1993-06-01), None
patent: WO 93/10847 (1993-06-01), None
patent: 07-505131 (1995-06-01), None
patent: 96/22114 (1996-07-01), None
patent: WO 97/14447 (1997-04-01), None
patent: 97/25085 (1997-07-01), None
patent: 9836784 (1998-08-01), None
patent: WO 99/47595 (1999-09-01), None
patent: 99/55396 (1999-11-01), None
patent: 0010622 (2000-03-01), None
patent: 0032255 (2000-06-01), None
patent: 00/57933 (2000-10-01), None
patent: WO 01/03607 (2001-01-01), None
patent: 0121229 (2001-03-01), None
patent: WO 01/21229 (2001-03-01), None
patent: WO 03/066119 (2003-08-01), None
Swartz, R., et al., “Biofilm Formation on Peritoneal Catheters Does Not Require the Presence of Infection,”ASAIO Trans., vol. 37, No. 4, Oct.-Dec. 1991, pp. 626-634.
Richards, G.K., et al., “Comparative Rates of Antibiotic Action AgainstStaphylococcus epidermidisBiofilms,”ASAIO Trans., vol. 37, No. 3, Jul.-Sep. 1991, pp. M160-M162.
Stamm, Walter E., “Catheter-Associated Urinary Tract Infections: Epidemiology, Pathogenesis, and Prevention,”American Journal of Medicine, vol. 91, No. 3B, Sep. 1991, pp. 65S-71S.
Golomb, Gershon, et al., “Prevention of Bacterial Colonization on Polyurethane in vitro by Incorporated Antibacterial Agent,”Journal of Biomedical Materials Research, vol. 25, No. 8, Aug. 1991, pp. 937-952.
Mulhall, Anne, “Biofilms and Urethral Catheter Infections,”Nursing Standard, vol. 5, No. 18, Jan. 23-29, 1991, pp. 26-28.
Chang, Chung Che, et al., “Effect ofStaphylococcus epidermidison Adherence ofPseudomonas aeruginosaandProteus mirabilisto Polymethyl Methacrylate (PMMA) and Gentamicin-Containing PMMA,”Journal of Orthopaedic Research, vol. 9, No. 2, Mar. 1991, pp. 284-288.
Liedberg, H., et al., “Pseudomonas aeruginosa: Adherence to and Growth on Different Urinary Catheter Coatings,”Internattonal Urology and Nephrology, vol. 22, No. 5, 1990, pp. 487-492.
Anwar, Hosmin, et al., “Testing the Susceptibility of Bacteria in Biofilms to Antibacterial Agents,”Antimicrobial Agents and Chemotherapy, Vo. 34, No. 3, 1990, pp. 2043-2046.
Dunne, W. Michael Jr., “Effects of Subinhibitory Concentrations of Vancomycin or Cefamandole on Biofilm Production by Coagulase-Negative Staphylococci,”Antimicrobial Agents and Chemotherapy, vol. 34, No. 3, Mar. 1990, pp. 390-393.
Doughterty, Steven H., et al., “Endogenous Factors Contributing to Prosthetic Device Infections,”Infectious Disease Clinics of N
Bucay-Couto Weenna
Li Jianmin
Miller Kathleen M.
Bonham David B.
Boston Scientific Scimed Inc.
Gherbi Suzette J
Mayer & Williams PC
Park Keum J.
LandOfFree
Implantable or insertable medical device resistant to... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Implantable or insertable medical device resistant to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Implantable or insertable medical device resistant to... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2625042