Implantable illuminator for photodynamic therapy of the breast a

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Light application

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606 16, A61B 1736

Patent

active

060275243

ABSTRACT:
A device for delivering phototherapeutic light to the nipple and surrounding tissue of a breast. Many mastectomy procedures for patients with breast cancer require removal of the nipple. Thus, for the best aesthetic result, post-operative augmentation or reconstruction of the breast includes the implantation of an artificial nipple. The present device and method permits a more conservative mastectomy to be performed while reducing the risk of recurrence wherein cancerous and pre-cancerous tissue in the nipple and surrounding aureole tissue are treated by illuminating the tissue with phototherapeutic light. The tissue is first perfused with a photosensitizer which accumulates therewithin. An embodiment of the device, which includes a rigid or semi-rigid hemispherical shell for structural stability, is attached to the breast. The device includes a transparent flexible aperture which is designed to fit snugly against the outer surface of the nipple and surrounding tissue. Phototherapeutic light from a light source enters the shell by means of a fiber optic and is conducted to a light diffuser tip disposed within the shell in optical communication with the light output end of the fiber optic. The light emanating from the diffuser tip is reflected from the interior surface of the hemispherical shell to uniformly illuminate the nipple and surrounding photosensitizer-laden tissue. In another embodiment a tissue expander is implanted within the breast following mastectomy. The tissue expander is adapted to receive light from a light source via a fiber optic and deliver diffuse phototherapeutic illumination to the tissue adjacent to and surrounding the tissue expander.

REFERENCES:
patent: 4612938 (1986-09-01), Dietrich et al.
patent: 4998930 (1991-03-01), Lundahl
patent: 5125925 (1992-06-01), Lundahl
patent: 5354293 (1994-10-01), Beyer et al.
patent: 5527308 (1996-06-01), Anderson et al.

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