Implantable glucose sensor

Surgery – Truss – Pad

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

128632, 204403, A61B 500

Patent

active

044310048

ABSTRACT:
A method and apparatus for more accurate measurements of the glucose content in body fuids by sensing the absolute level of oxygen concentration in the fluid and correcting the output differential measurement indicative of the glucose content in the fluid according to the absolute level of oxygen.
In the two electrode systems known to the art, the unaltered oxygen electrode of the electrode pair may be employed to read the absolute level of oxygen concentration and in addition, function to establish the difference in oxygen concentration caused by glucose oxidation.
In view of the fact that temperature may vary, a thermistor may be included in the electrode system to make temperature corrections for reason that the absolute oxygen reading from either a polarographic or galvanic oxygen electrode is extremely sensitive to temperature and the rate of glucose oxidation is temperature sensitive.

REFERENCES:
patent: 3770607 (1973-11-01), Williams
patent: 3920969 (1975-11-01), Berglas
patent: 4240438 (1980-12-01), Updike et al.
patent: 4301807 (1981-11-01), Mentelos
Kondo et al., "Trial of New Vessel Access Type Glucose Sensor for Implant. Art. Pancreas in Vivo"; Trans. Am. Soc. Artif. Intern. Organs, vol. XXVII, 1981, pp. 250-252.
Pagurek et al., "Adaptive Control of Human Glucose-Regulatory System"; Med. and Biol. Engr., vol. 10, No. 6, 11-1972, pp. 752-761.
Chang et al., "Validation and Bidengr. Aspects of an Implant. Glucose Sensor"; Trans. Am. Soc. Artif. Int. Organs; vol. XIX, 1973, pp. 352-360.
Chua et al., "Plasma Glucose Measurement with the Yellow Springs Glucose Analyzer"; Clin. Chem. 24/1, pp. 150-152, 1978.
Danielsson et al.; "Use of an Enzyme Thermistor in Continuous Measurements and Enzyme Reactor Control"; Biotechnology and Bioengineering, vol. 21, pp. 1749-1766, 1979.
Bessman et al.; "Implantation of a Closed Loop Artificial Beta Cell in Dogs"; Trans. Am. Soc. Artif. Inter. Organs; vol. 28, 1981, pp. 7-18.
Mahler et al., "Kinetics of Enzyme-Catalyzed Reactions"; Biol. Chem.; 1966, pp. 237-241.
Clark et al.; "Differential Anodic Enzyme Polarography for the Measurement of Glucose"; Adv. Exp. Med. Biol.; 37A, pp. 127-133, 1973.
Updike et al., "The Enzyme Electrode"; Nature, vol. 214, 6-1967, pp. 986-988.
Wingard et al., "Immobilized Enzyme Electrodes for the Potentiometric Measurement of Glucose Concentration"; Journ. of Biomed. Mat'ls Res., vol. 13, pp. 921-935, 1979.
Layne et al.; "Continuous Extracorporeal Monitoring of Animal Blood Using the Glucose Electrode"; Diabetes 25, pp. 81-89, 2-1976.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Implantable glucose sensor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Implantable glucose sensor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Implantable glucose sensor will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2369830

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.