Surgery – Controlled release therapeutic device or system – Implanted dynamic device or system
Reexamination Certificate
2000-03-09
2002-10-15
Walberg, Teresa (Department: 3742)
Surgery
Controlled release therapeutic device or system
Implanted dynamic device or system
Reexamination Certificate
active
06464687
ABSTRACT:
TECHNICAL FIELD OF THE INVENTION
This invention is related to body implantable systems, and more particularly to miniature electronic components for use in delivering drugs into patients.
BACKGROUND OF THE INVENTION
There is a large population of people and animals who would greatly benefit from the ability to have an implanted drug delivery device. Many delivery devices have been developed, but few have found widespread clinical use because of the large size required. Drug delivery systems have long been used to provide patients with appropriate dosages of drugs over extended periods. Implantable devices have the advantage of assuring patient compliance and delivery accuracy, as well as the ability to create high local concentrations of medications without systemic side effects such as those occurring with chemotherapeutic drugs. These advantages make local, implantable drug delivery the most effective treatment for many therapeutic regimens. This application discloses a drug delivery system based on programmable intervals similar to the following patents: U.S. Pat. No. 4,731,051 entitled “Programmable Control Means For Providing Safe And Controlled Medication Infusion,” issued Mar. 15, 1988; U.S. Pat. No. 5,041,107 entitled “Electrically Controllable Non-Occluding, Body Implantable Drug Delivery System,” issued Aug. 20, 1991; and U.S. Pat. No. 4,003,379 entitled “Apparatus And Method For Implanting Self-Powered Medication Dispensing,” issued Jan. 18, 1977, all of the disclosures of which are herein incorporated by reference.
This application also discloses methods to deliver drugs based on a sensed physiological need, examples being described in the following patents: U.S. Pat. No. 5,474,552 entitled “Implantable Drug Delivery Pump,” issued Dec. 12, 1995; U.S. Pat. No. 4,055,175 entitled “Blood Glucose Control Apparatus,” issued Oct. 25, 1977; U.S. Pat. No. 5,190,041 entitled “System For Monitoring And Controlling Blood Glucose,” issued Mar. 2, 1993; and U.S. Pat. No. 5,658,250 entitled “Systems And Methods For Operating Ambulatory Medical Devices Such As Drug Delivery Devices,” issued Aug. 19, 1997, the contents of which are hereby incorporated by reference.
SUMMARY OF THE INVENTION
The present invention disclosed and claimed herein, in one aspect thereof, is a system for delivering a drug to a patient. The system comprises a drug storage medium for storing a drug; and one or more aggregations of semiconductor devices operatively connected to the drug storage medium for monitor and control of the dispensing of the drug. The system is then implanted in the body of the patient at a drug delivery site for delivery of the drug to said site.
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Ahn Samuel S.
Ahn Suzanne I.
Gaffney F. Andrew
Hayes Steven R.
Ishikawa Akira
Ball Semiconductor Inc.
Howison Thoma & Arnott, L.L.P.
Robinson Daniel
Walberg Teresa
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