Implantable drug delivery prosthesis

Details Implantable drug delivery prosthesis Implantable drug delivery prosthesis

2005-12-27

2005-12-27

Prebilic, Paul B. (Department: 3738)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Stent structure

C623S001420, C623S001430

Reexamination Certificate

active

06979347

ABSTRACT:
An apparatus and associated method for delivering a therapeutic substance to a vascular lumen, using an implantable prosthesis, such as a stent, which has grooves or trenches formed thereon. The grooves are formed on specific regions of the stent struts to increase the flexibility of the stent. The grooves also provide a therapeutic material carrying capability for treating intravascular ailments, such as instent restenosis and thrombosis. The therapeutic material loading of the grooves can be accomplished in several ways. For example, a pure therapeutic material or a pre-mixed material with a polymer solution, which enhances the adhesion properties of the material, may be deposited directly in to the grooves using conventional spray or modified dip techniques. In another example, a microextruded monofilament therapeutic material can be wound about the stent, such that the monofilament becomes embedded in the grooves.

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Microtruder Technology Bulletin; www.randcastle.com; Mar. 14, 2000; 8 pages.

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