Implantable controlled release device to deliver drugs directly

Details Implantable controlled release device to deliver drugs directly Implantable controlled release device to deliver drugs directly

1995-09-27

1998-06-30

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424427, 5147722, 5147723, 6048901, 6048921, 623 6, A61F 202, A61F 214, A61K 4730, A61K 922

Patent

active

057730199

ABSTRACT:
A simple and implantable sustained release drug delivery device with an inner core containing an effective amount of a low solubility agent covered by a non-bioerodible polymer coating layer that is permeable to the low solubility agent is disclosed. A method for treating a mammal to obtain a desired local or systemic physiological or pharmacological effect by surgically implanting such a sustained release drug delivery device into a mammal in need of treatment is also disclosed.

REFERENCES:
patent: 3416530 (1968-12-01), Ness
patent: 3832252 (1974-08-01), Higuchi et al.
patent: 3845201 (1974-10-01), Haddad et al.
patent: 3870791 (1975-03-01), Haddad et al.
patent: 4300557 (1981-11-01), Refojo et al.
patent: 4309776 (1982-01-01), Berguer
patent: 4309996 (1982-01-01), Theeuwes
patent: 4649047 (1987-03-01), Kaswan
patent: 4808353 (1989-02-01), Nambu et al.
patent: 4923699 (1990-05-01), Kaufman
patent: 4942035 (1990-07-01), Churchill et al.
patent: 4973304 (1990-11-01), Graham et al.
patent: 5091185 (1992-02-01), Castillo et al.
patent: 5128144 (1992-07-01), Korsatko-Wabnegg et al.
patent: 5137728 (1992-08-01), Bawa
patent: 5156851 (1992-10-01), Castillo et al.
patent: 5164188 (1992-11-01), Wong
patent: 5178635 (1993-01-01), Gwon et al.
patent: 5229128 (1993-07-01), Haddad et al.
patent: 5232708 (1993-08-01), Castillo et al.
patent: 5342620 (1994-08-01), Chowhan
patent: 5378475 (1995-01-01), Smith et al.
Pearson, P.A., et al.; "Sustained Delivery and Clearance of Intraocular Cyclosporine"; Investigative Opthalmology and Visual Science, vol. 34, Issue No. 7, (1993); Abstract No. 3917-31.
Baker, C.W., et al.; "In Vitro And In Vivo Evaluation of Intravitreal Sustained Release Dexamethasone Devices"; Investigative Opthalmology and Visual Science, vol. 34, Issue No. 7, (1993); Abstract N0. 3919-33.
Guo, H., et al.; "Sustained Device for Coadministration of Suramin and Amiloride"; Investigative Ophthalmology and Visual Science, vol. 36, No. 4, Mar. 15, 1995; Abstract No. 779-687.
Cordahi, G.J., et al.; "Toxicity of Sustained Release Cyclosporin A in Non-Human Primate Eyes", Investigative Ophthalmology and Visual Science, vol. 36, No. 4, Mar. 15, 1995; Abstract No. 2509-476.
Cheng, C.K., et al.; "Intravitreal Sustained Release Dexamethasone Device in the Treatment of Experimental Uveitis", Investigative Opthalmology and Visual Science, vol. 35, No. 4, Abstract No.3370-4:00.
Enyedi, L.B., et al.; Pharmacokinetics and Toxicity of an Intravitreal Device Providing Sustained Release of Cyclosporine(CsA) and Dexamethasone(dex); Investigative Opthalmology and Visual Science, vol. 35, No. 4, Abstract No. 3015-8:30.
Bierly, J.R., et al.; "Inhibition of Corneal Neovascularization with Subconjunctival Sustained Release Trihydroxysteroid Implants"; Investigative Opthalmology and Visual Science, vol. 35, No. 4, Abstract No. 444-55.
Hainsworth, D.P., et al.; "Intravitreal Ciprofloxacin Via a Bioerodible Sustained Release Device"; Investigative Opthalmology and Visual Science, vol. 35, No. 4, Abstract No. 3421-7:15.
Pearson, P.A., et al.; "Sustained Delivery of Cyclosporine(CsA) and Dexamethasone(dex) in the Treatment of Experimental Proliferative Vitreoretinopathy", Investigative Opthalmology and Visual Science, vol. 35, No. 4, Abstract No. 3085-12:00.
Cheng, C., et al.; "Intravitreal Sustained-Release Dexamethasone Device in the Treatment of Experimental Uveitis"; Investigative Opthalmology and Visual Science, vol. 36, No. 2, Feb. 1995.

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