Implantable capsule for enhancing cell electric signals

Details Implantable capsule for enhancing cell electric signals Implantable capsule for enhancing cell electric signals

1997-04-09

2000-07-18

Winakur, Eric F.

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

128899, 156 60, 427214, 427256, 264 41, B61B 505, B29C 6500

Patent

active

060919744

ABSTRACT:
A capsule for encapsulating implantable cells for improving the detectability of electrical signals generated by the cells is provided. The capsule includes a low-conductivity (high electrical resistance) membrane and a semi-permeable (low electrical resistance) membrane. The low-conductivity membrane seals around the circumference of the cell mass between the electrical poles of the capsule, and further extends for increasing the electrical resistance between the poles. The semi-permeable membrane enables nutrients and waste materials to flow to and from the cell mass. The semi-permeable membrane enclosed at least one of the poles of the cell mass, and cooperates with the low-conductivity membrane to completely enclose the cell mass. The low-conductivity membrane may enclose one of the poles, if desired. Electrodes are used to detect the electrical signals from the cell mass. Various methods of making the capsule are disclosed.

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