Implantable, biocompatible reservoirs permitting conservation, c

Surgery – Controlled release therapeutic device or system – Implanted dynamic device or system

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530356, A61K 922

Patent

active

046700145

ABSTRACT:
Biocompatible reservoirs are constituted by collagen, optionally associated with mucopolysaccharides and/or gelatin; these reservoirs can be filled with an active principle which does not have to be mixed with collagen. The reservoirs can be employed to either hold or to emit one or more active principles in order to concentrate same and/or to distribute same at a controlled rate "in vitro" and/or "in vivo". The reservoirs thus are enclosed vessels of conseration of "in vitro" or "in vivo" cultures of cells, bacteria or viruses.

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Rubin et al., Collagen as a Vehicle for Drug Delivery in: The Journal of Clinical Pharmacology, Aug.-Sep., 1973, pp. 309-312

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