Implantable biocompatable immunoisolatory vehicle for delivery o

Details Implantable biocompatable immunoisolatory vehicle for delivery o Implantable biocompatable immunoisolatory vehicle for delivery o

1998-09-04

2000-07-04

Azpuru, Carlos A.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424493, 424497, 264 41, 435 11, 435177, 435178, 435179, 435180, 435182, A61F 202

Patent

active

060835230

ABSTRACT:
An immunoisolatory vehicle for the implantation into an individual of cells which produce a needed product or provide a needed metabolic function. The vehicle is comprised of a core region containing isolated cells and materials sufficient to maintain the cells, and a permselective, biocompatible, peripheral region free of the isolated cells, which immunoisolates the core yet provides for the delivery of the secreted product or metabolic function to the individual.

REFERENCES:
patent: 3093831 (1963-06-01), Jordan
patent: 3615024 (1971-10-01), Michaels
patent: 4298002 (1981-11-01), Ronel
patent: 4352883 (1982-10-01), Lim
patent: 4353888 (1982-10-01), Sefton
patent: 4409331 (1983-10-01), Lim
patent: 4479796 (1984-10-01), Kallok
patent: 4670014 (1987-06-01), Huc
patent: 4686098 (1987-08-01), Kopchick
patent: 4689293 (1987-08-01), Goosen
patent: 4749620 (1988-06-01), Rha
patent: 4789550 (1988-12-01), Hommel
patent: 4806355 (1989-02-01), Goosen
patent: 4868121 (1989-09-01), Scharp
patent: 4883666 (1989-11-01), Sabel
patent: 4892538 (1990-01-01), Aebischer
patent: 4902295 (1990-02-01), Walthall
patent: 4942129 (1990-07-01), Goosen
patent: 4960415 (1990-10-01), Reinmuller
patent: 5002661 (1991-03-01), Chick
patent: 5026365 (1991-06-01), Rossini
patent: 5082670 (1992-01-01), Gage
patent: 5084350 (1992-01-01), Chang
patent: 5106627 (1992-04-01), Aebischer
patent: 5156844 (1992-10-01), Aebischer
patent: 5292515 (1994-03-01), Moro
*Aebischer et al., Trans. Am. Soc. Artif. Intern. Organs, vol. XXXII, pp. 134-137 (1986).
*Aebischer et al., Biol. Abstr., 91, p. 762 (1991).
*Aebischer et al., Biomaterials, 12 pp. 50-56 (1991).
*Aebischer et al., Brain Research, 560, pp. 43-49 (1991).
*Aebischer et al., Exn. Neurol., 111, pp. 269-275 (1991).
*Aebischer et al., J. Biomech. Eng., 113, pp. 178-183 (1991).
*Aebischer and Goddard, Science, 252, p. 133 (1991).
*Algire et al., J. National Cancer Institute, 15, pp. 493-507 (1954).
*Altman et al., Trans. Am. Soc. Artif. Intern. Organs, vol. XXX, pp. 382-386 (1984).
*Altman et al., Diabetes, 35, pp. 625-633 (1986).
*Amicon Corp. Publication No. 442C, pp. 1-4.
*Archer et al., J. Surgical Research, 28, pp. 77-85 (1980).
*Bontempo et al., Blood, 69, pp. 1721-1724 (1987).
*Brandrup et al., Polymer Handbook 3rd Ed., John Wiley & Sons, N.Y. (1989).
*Britt et al., Diabetes, 30, pp. 580-583 (1981).
*Cabasso, Encyclopedia of Chemical Technology, Kirk Othmer, ed., Wiley, NY, 12, pp. 492-517 (1980).
*Cai et al., Artificial Organs, 12, pp. 388-393 (1988).
*Cepko, Neuron, 1, pp. 345-353 (1988).
*Christenson et al., J. Biomed. Mat. Res., 23, pp. 705-718 (1989).
*Christenson, Ph.D. Thesis, Brown University (1990).
*Cohen et al., J. Am. Chem. Soc., 112, pp. 7832-7833 (1990).
*Cole et al., Diabetologia, 35, pp. 231-237 (1992).
*Darguy et al., Diabetologia, 28, pp. 776-780 (1985).
*Darquy et al., Trans. Am. Soc. Artif. Intern. Organs, vol. XXXIII, pp. 356-358 (1987).
*Dionne, Thesis Ph.D., Massachusetts Institute of Technology, pp. 170-184 (1989).
*Dupuy et al., J. Biomed. Mat. Res., 22, pp. 1061-1070 (1988).
*Edmunds et al., Applied Biochemistry and Biotechnology, 20-21, pp. 603-619 (1989).
*Faithfull, Anaesthesia, 42, pp. 234-242 (1987).
*Fan et al., Diabetes, 39, pp. 519-522 (1990).
*Fu et al., Transplantation, 47, pp. 432-435 (1989).
*Gordon et al., Nature, 326, pp. 403-405 (1987).
*Hama et al., Pain, 52, pp. 223-231 (1993).
*Hoffman et al., Exp. Neurol., 110, pp. 39-44 (1990).
*Hong et al., Int. J. Radiation Oncology Biol. Phys. 16, pp. 1097-1099 (1989).
*Iwata et al., Diabetes, 38, pp. 224-225 (1989).
*Jaeger et al., Progress in Brain Research, 82, pp. 41-46.
*Elsevier Science Publishers B.V. (1990).
*Jaeger et al., Brain Research, 551, pp. 163-170 (1991).
*Jarret et al., The Lancet, 2, pp. 1009-1012 (1976).
*Jolley et al., Transplantation Proceedings, IX, pp. 363-365 (1977).
*Klomp et al., Journal of Biomedical Materials Research, 17, pp. 865-871 (1983).
*Lacy et al., Science, 204, pp. 312-313 (1979).
*Lacy et al., Science, 254, pp. 1782-1784 (1991).
*Land et al., Nature, 304, pp. 596-602 (1983).
*Leung et al., Artificial Organs, 7, pp. 208-212 (1983).
*Lim et al., Science, 210, pp. 908-910 (1980).
*Livett, Physiology Reviews, 64, pp. 1103-1161 (1984).
*Maniats et al., Can. J. comp. Med., 42, pp. 428-437 (1978).
*Matthews et al., Recent Advances in Germfree Research.
*Tokai University Press, pp. 61-64 (1981).
*NASA Tech. Briefs MSC-21480, U.S. Gov't. Printing Office, Washington, D.C.
*NASA Tech. Briefs NPO-17517, vol. 15 #1 p. 54, U.S. Gov't. Printing Office, Washington, D.C.
*O'Shea et al., Biochim. Biophys. Acta, 804, pp. 133-136 (1984).
*O'Shea et al., Diabetes, 35, pp. 943-946 (1986).
*Reach, Biomed. Biochim. Acta, 43, pp. 569-576 (1984).
*Ricordi et al., Transplantation, 45, pp. 1148-1151 (1988).
*Ronel et al., Journal of Biomedical Materials Research, 17, pp. 855-864 (1983).
*Sagen et al., Proc. Natl. Acad. Sci. USA, 83, pp. 7522-7526 (1986).
*Sagen et al., Pain, 42, pp. 69-79 (1990).
*Sagen et al., J. Neuroscience, 13, pp. 2415-2423 (1993).
*Sanberg et al., Exp. Neurol., 66, pp. 444-4-4466 (1979).
*Scharp et al., World J. Surg., 8, pp. 221-229 (1984).
*Sefton et al., Biotech. and Bioeng., XXIX, pp. 1135-1143 (1987).
*Short et al., Dev. Neurosci., 12, pp. 34-35 (1990).
*Soeldner et al., Diabetes, 14, pp. 771-779 (1965).
*Sugamori et al., Trans. Am. Soc. Artif. Intern. Organs, XXXV, pp. 791-799 (1989).
*Sun et al., Diabetes, 26, pp. 1136-1139 (1977).
*Sun et al., Applied Biochem. Biotechnol., 10, pp. 87-99 (1984).
*Sun et al., Trans. Am. Soc. Artif. Intern. Organs, XXXII, pp. 39-41 (1986).
*Sun et al., Biomat. Art. Cells. Art. Org., 15, pp. 483-496 (1987).
*Sun et al., CRC Critical Reviews in Therapeutic Drug Carrier Systems, 4, pp. 1-12 (1987).
*Sun, Trans. Am. Soc. Arfif. Intern. Organs, XXXIII, pp. 787-790 (1987).
*Sun, Methods in Enzymology, 137, pp. 575-580 (1988).
*Tresco et al., ASAIO Journal, 38, pp. 17-23 (1992).
*Tze et al., Nature, 264, pp. 466-467 (1976).
*Tze et al., Diabetologia, pp. 247-252 (1979).
*Tze et al., Transplantation, 33, pp. 563-564 (1982).
*Weber et al., Transplantation, 49, pp. 396-404 (1990).
*Winn et al., Exp. Neurol., 105, pp. 244-250 (1989).
*Winn et al., J. Biomed. Materials Res., 23, pp. 31-44 (1989).
*Winn et al., Exp. Neurol., 113, pp. 322-329 (1991).
*Winnie et al., Anesthesiology, 79, pp. 644-653 (1993).
*Wu et al., Int'l. J. Pancreatology, 3, pp. 91-100 (1988).
*Wu et al., Trans. Am. Soc. Artif. Intern. Organs, XXXV, pp. 736-738 (1989) .

Affiliated with

Also associated with

Rating

Implantable biocompatable immunoisolatory vehicle for delivery o does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Implantable biocompatable immunoisolatory vehicle for delivery o, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Implantable biocompatable immunoisolatory vehicle for delivery o will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1483596