Implant material composition, preparation thereof as well as use

Details Implant material composition, preparation thereof as well as use Implant material composition, preparation thereof as well as use

1990-10-19

1993-03-23

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424423, 623 16, A61F 228

Patent

active

051962012

ABSTRACT:
The invention relates to an implant material composition, its preparation, and its use for restoring bone tissue in a human or animal body. The composition comprises a particulate biocompatible bone tissue substitute material distributed in a bioacceptable mixture of (a) a water-based liquid, (b) a monoglyceride, and optionally (c) a triglyceride. The ingredients (a), (b) and (c) form an L2-phase or a lamellary liquid crystalline phase, and are present in such proportions within said phases that they are capable of being transformed into a cubic liquid crystalline phase or a reversed hexagonal liquid crystalline phase when contacted with an aqueous liquid. The phase conversion imparts to the composition such a high viscosity that it functions as an implant material as defined.

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