Implant material

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

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Details

C514S008100, C514S035000, C514S037000, C514S039000, C514S253080

Reexamination Certificate

active

07858109

ABSTRACT:
Form bodies, which can be rotationally-symmetrical or irregularly-shaped, consist of at least one member of the group of the antibiotic salts, gentamicin myristate, gentamicin palmitate, gentamicin stearate, tobramycin myristate, tobramycin palmitate, tobramycin stearate, amikacin myristate, amikacin palmitate, amikacin stearate, vancomycin palmitate, vancomycin stearate, ramoplanin palmitate, ramoplanin stearate, levofloxacin palmitate, levofloxacin stearate, ofloxacin palmitate, ofloxacin stearate, moxifloxacin palmitate, moxifloxacin stearate, clindamycin palmitate, and clindamycin stearate. A medical device for implantation, in which the form bodies are arranged on a biodegradable filament at a distance of 1 mm to 25 mm as well as a method for the manufacture of the medical device and the use of the form bodies or the medical device to treat chronic osteomyelitis are described.

REFERENCES:
patent: 5756127 (1998-05-01), Grisoni et al.
patent: 7030093 (2006-04-01), Vogt et al.
patent: 2003/0004491 (2003-01-01), Tenhuisen et al.
patent: 2006/0035376 (2006-02-01), Geltser
patent: 26 51 441 (1978-05-01), None
patent: 30 37 2701 (1982-05-01), None
Resorbable Antibiotic Coatings for Bone Substitutes and Implantable Devices. Vogt et al. (submitted in IDS).
Antibiotic-Impregnated Heart Valve Sewing Rings for Treatment and Prophylaxis of Bacterial Endocarditis. Cimbollek et al. (submitted in IDS).
S. Vogt, Resorbable Antibiotic Coatings for Bone Substitutes and Implantable Devices, 2005, pp. 814-819.

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