Implant having integrally-textured, hemocompatible, blood-contac

Plastic and nonmetallic article shaping or treating: processes – Direct application of electrical or wave energy to work – Conveying or aligning particulate material

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264102, 264221, 264225, 264226, 264227, 264317, 264255, 264571, 264DIG44, B29C 3342, B29C 3352

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active

059977965

ABSTRACT:
An implant having an integrally-textured, hemocompatible blood-contacting surface and a method for producing the same is provided. The implantable device can include a device body having a textured surface and a predefined complex shape, such as a bladder or a generally U-shaped conduit. The device body can be composed of a first device material, and the textured surface can be formed of a second device material on the obverse side of the device. The textured surface can have multiple, blood-compatible structures integrally formed thereon. The structures can be fibrils that are suitable for a generally uniform biological layer to be established thereupon. The method for producing an implantable device can include the steps of fabricating a mold; applying a flock to the mold; introducing a conformable dissoluble material to the mold; removing the dissoluble material from the mold; removing the flock from the dissoluble material using a first solvent thereby creating a dissoluble device form having a form surface having multiple invaginations therein; applying a layer of a selected device material to the dissoluble device form thereby providing a device wall with the structures being integrally formed thereon; and removing the dissoluble device form from the device wall by liquefying the device form, thereby providing the implantable device.

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"Fabrication and Testing of Flocked Blood Pump Bladders", by Victor Poirier. Thermo Electron Corporation, Waltham, Massachusetts.
"Polyester Fibril Flocked Surface for Blood Pumps", by H. Harasald, A. Field, N. Sato, J. Snow, R. Kiraly and Y. Nose, Trans. Am Soc. Artif. Intern. Organs, vol. XXIX, 1983.
"Development and Testing of Flocking Materials", by M. Szycher, W.F. Bernhard, v. Poirier, C. Franzblau, C.C. Haudenschild, Thermo Electron Corporation, Waltham, Massachusetts, prepared for National Heart, Lung and Blood Institute, Bethesda, MD, Apr. 1979.

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