Implant for filling bone cavities and fixing bone fragments in a

Details Implant for filling bone cavities and fixing bone fragments in a Implant for filling bone cavities and fixing bone fragments in a

1984-06-22

1986-09-09

McCarthy, Helen M.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

128 92C, 264 44, 264 60, 424 19, 424 80, 424150, 604890, 604891, 623 66, A01N 2526

Patent

active

046106928

ABSTRACT:
A sintered tricalcium phosphate implant for filling bone cavities and for fixing bone fragments is provided, which comprises a discretely-shaped, porous body, at least one therapeutically-active ingredient impregnated into this porous body and distributed among the pores therein, and at least one coating of predetermined thickness of a biodegradable substance on at least a portion of this porous body, so that the time of absorption of the therapeutically-active ingredient is controlled by the thickness of the biodegradable substance. A process for producing this sintered tricalcium phosphate implant is also provided, along with an implant system for filling bone cavities and for fixing bone fragments in a living body, comprising a number of such tricalcium phosphate bone implants, with discrete coatings of biodegradable substance of predetermined thicknesses over at least some of the porous bodies constituting the tricalcium phosphate bone implants.

REFERENCES:
patent: 4322398 (1982-03-01), Reiner et al.
patent: 4330891 (1982-05-01), Branemark et al.
patent: 4347234 (1982-08-01), Wahlig et al.
patent: 4371484 (1983-02-01), Inukai et al.
patent: 4401651 (1983-08-01), Knutson
patent: 4449981 (1984-05-01), Drake et al.
patent: 4497075 (1985-02-01), Niwa et al.
Eitenmuller, J. et al. "Experimental and Preliminary Clinical Experience with Absorbable Calcium Phosphate Granules Containing an Antibiotic or Antiseptic for the Local Treatment of Osteomyelitis" Journal of Hospital Infection (1985)(Supplement), pp. 177-184.
The Merck Index-9th Ed., 1976, pp. 996-997, Items 7498 and 7499.

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