Implant fixation

Details Implant fixation Implant fixation

1988-11-23

1992-04-28

Cannon, Alan W.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Miscellaneous

623 16, 424549, 514 2, 514 12, 514 21, A61F 228, A61K 3700

Patent

active

051084368

ABSTRACT:
Stress-bearing prostheses for replacement or partial replacement of stress-bearing bone are fixed in place by bony ingrowth by providing a stress-bearing member having a porous region in combination with an osteogenic factor extract or a purified osteogenic inductive protein, optionally in combination with a TGF-beta cofactor, in a pharmaceutically acceptable carrier. The carrier is preferably either a collagen composition or a ceramic.

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Sampath et al., Proc. Natl. Acad. Sci. (1987) 84:7109-7113.
Bentz et al., Development and Diseases of Cartilage and Bone Matrix (1987) Alan R. Liss, et al., pp. 137-147.

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