Implant depots to deliver growth factors to treat...

Details Implant depots to deliver growth factors to treat... Implant depots to deliver growth factors to treat...

2006-05-05

2010-11-16

Kemmerer, Elizabeth C. (Department: 1646)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

C623S017110, C424S198100, C514S002600

Reexamination Certificate

active

07833270

ABSTRACT:
The present invention relates to the design and composition of a depot implant for optimal delivery of growth factors to treat osteoporotic bone, in that such depot implant is constructed to be in a cylinder (rod) or sphere shape and have a natural or synthetic polymer scaffold with or without impregnated calcium phosphate particles. The density of the depot is higher than a typical BMP sponge carrier to facilitate it's implantation and slower release of the growth factor. The scaffold is such that it has adequate porosity and pore size to facilitate growth factor seeding and diffusion throughout the whole of the bone structure resulting in increased bone mineral density in the osteoporotic bone. In addition, the shape of the depot implant allows for delivery through a cannula or large bore needle.

REFERENCES:
patent: 5344654 (1994-09-01), Rueger et al.
patent: 5972384 (1999-10-01), Thut et al.
patent: 5972385 (1999-10-01), Liu et al.
patent: 6004573 (1999-12-01), Rathi et al.
patent: 6274159 (2001-08-01), Marotta et al.
patent: 6346123 (2002-02-01), McKay
patent: 6371988 (2002-04-01), Pafford et al.
patent: 6375935 (2002-04-01), Constantz
patent: 6613091 (2003-09-01), Zdeblick et al.
patent: 2004/0167637 (2004-08-01), Biscup
patent: 2005/0084542 (2005-04-01), Rosenberg et al.
patent: 2005/0152949 (2005-07-01), Hotchkiss et al.

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