Impaired wound healing compositions and treatments

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C536S023100, C536S024200, C536S024500, C435S006120, C435S375000

Reexamination Certificate

active

08063023

ABSTRACT:
Connexin modulation for the treatment of wounds that do not heal at expected rates, including delayed healing wounds, incompletely healing wounds, and chronic wounds, and associated methods, compositions and articles.

REFERENCES:
patent: 5044810 (1991-09-01), Matsuoka et al.
patent: 5166195 (1992-11-01), Ecker
patent: 7098190 (2006-08-01), Becker et al.
patent: 7153822 (2006-12-01), Jensen et al.
patent: 2005/0119211 (2005-06-01), Chowrira
patent: WO 96/19194 (1996-06-01), None
patent: WO 98/24797 (1998-06-01), None
patent: WO 00/44409 (2000-08-01), None
patent: WO 03/063891 (2003-08-01), None
patent: WO 2005/053600 (2005-06-01), None
patent: WO 2005/119211 (2005-12-01), None
patent: WO 2006/069181 (2006-06-01), None
patent: WO 2006/134494 (2006-12-01), None
patent: WO 2008/060622 (2008-05-01), None
patent: WO 2008/073479 (2008-06-01), None
patent: WO 2008/073479 (2008-06-01), None
patent: WO 2008/151022 (2008-12-01), None
patent: WO 2009/075881 (2009-06-01), None
patent: WO 2009/075882 (2009-06-01), None
patent: WO 2009/075882 (2009-06-01), None
Doughty, D. B., Advances in Skin & Wound Care, vol. 17:442-444, 2004.
Serena et al., “Acceleration of Venous Ulcer Healing Using a Topical Eonnexin43 Antisense Compound: Phase 2 Results,” Symposium on Advanced Wound Care (Apr. 14-17) (Abstract Supp. at BRG.23).
Sibbald et al. Venous leg ulcers, in Chronic Wound Care: A Clinical Source Book for Healthcare Professionals (Krasner DL, Rodeheaver GT, Sibbald RG, eds., HMP Communications, 4th ed. 2007) 429-442, 429.
Sheehan, et al. “Percentage Change in Wound Area of Diabetic Foot Ulcers Over a 4-Week Period Is a Robust Predictor of Complete Healing in a 12-week Prospective Trial,” Diabetes Care 26(6):1879-1882 (June 203).
Safety and Effectiveness Data for Apligraf™, available at http://www.accessdata.fda.gov/cdrh—docs/pdf/P950032S016b.pdf, Jun. 20, 2000.
U.S. Department of Health and Human Services Food and Drug Administration. “Guidance for Industry: Chronic Cutaneous Ulcer and Burn Wounds—Developing Products for Treatment,” (Jun. 2006).
Coda Therapeutics News Release, “CoDa Therapeutics Achieves Positive Phase 2 Efficacy of NEXAGON® in Chronic Venous Leg Ulcers,” and available at http://www.codatherapeutics.com
ews-nexagon.html (May 25, 2010).
Requirement for Restriction/Election, U.S. Appl. No. 12/001,498, Mail Date Apr. 22, 2009.
EP Search Report & Opinion—EP 05016736.0—Dec. 19, 2005.
Written Opinion—PCT/US2007/025446—Mail Date Jun. 16, 2009.
Collaborative Neuroscience the Spinal Cord Injury Project. Care Cure Community Postings for “Gel ‘is helping wounds heal in half the time’
exagon.” Sep. 29, 2006 http://sci.rutgers.edu/forum/showthread.php?t=6653.
“A chinese procedure involving stem cell transplants is providing some very interesting results.” Oct. 24, 2003. Canadian Paraplegic Association. Sep. 27, 2006 http://www.canparaplegic.org
ational/level12.tpl?var1=story&var2=20031024154627.
“News bio-active gel cuts wound healing time in half.” Oct. 20, 2003. UCL Media Relations. University College London. Sep. 29, 2006 http://www.ucl.ac.uk/media/library
exagon0.
“Nice blurb on biologics on cbsnews.com.” Laxat. Sep. 9, 2006 http://www.laxat.com/Nice-blurb-on-biologics-on-cbsnews-com-1219610.html.
“Welcome to the lab of David Becker and Jeremy Cook.” Becker/Cook Lab. May 26, 2006 http://www.anat.ucl.ac.uk/research/becker/people.htm.
“Wound-healing technology shortlisted for award.” UCL News. University College London. Sep. 27, 2006 http://www.ucl.ac.uk
ews-archive/archive/2003/october-2003/latest
ewsitem.shtml?0309....
A.C. de Carvalho, et al., J Cardiovasc Electrophysiol 5:686 (1994).
Abdulla, KM, et al. Endocrine 10:35-41 (1999).
Agrawal, Tibtech 14:376-387 (Oct. 1996).
Altschul S.F. J Mol Biol 215:403-10 (1990).
Altschul S.F. J Mol Evol 36:290-300 (1993).
Baldwin, Heather C., et. al., “Growth factors in corneal wound healing following refractive surgery: A Review” ACTA Ophthalmologica Scandinavica 80(3):Jun. 2002.
BBC News “Gels heal wounds more quickly”; http:/
ews.bbc.co.uk/1/hi/health/3243633.stm. (May 26, 2006).
Becker DL, Green CR (2001) Gap junction-mediated interactions between cells. Chapter 3 inCell-Cell Interactions—A Practical Approached. TP Fleming. Oxford University Press, pp. 47-70.
Becker, D.L. and Davies, C.S. (1995) The role of gap junctions in the development of the preimplantation mouse embryo. InMicroscopy of Intercellular Communicating Junctions. Ed. R. Goúrdie. Microsc. Res. Tech. 31, 364-374.
Becker, D.L. and Mobbs, P. (1999) Connexin alpha1 and cell proliferation in the developing chick retina. Expl. Neurol. 156(2): 326-332.
Becker, D.L. et al. Roles for a1 connexin in morphogenesis of chick embryos revealed using a novel antisense approach. Devel. Genetics, 24:33-42, 1999.
Becker, D.L., Bonness, V., and Mobbs, P. (1998) Cell coupling in the retina: Patterns and purpose. Cell Biol. Int. 22, 781-792.
Becker, D.L., Bonness, V., Catsicas, M. and Mobbs, P. (2002) Changing patterns of ganglion cell coupling and connexin expression during chick retinal development. J. Neurobiol. 52, 280-293.
Becker, D.L., Ciantar, D., Catsicas, M., Pearson, R. and Mobbs, P. (2002) Use of pIRES vectors to express EGFP and connexin constructs in studies of the role of gap junctional communication in the early development of the chick retina and brain. Cell Commun. Adhes. 8, 355-359.
Becker, D.L., Cook, J.E., Davies, C.S., Evans, W.H. and Gourdie, R. (1998) Expression of major gap junction connexin types in the working myocardium: Mammals are not typical vertebrates. Cell Biol. Int. 22, 527-543.
Becker, D.L., David-Leclerc, C. and Warner A.E. (1992) “The relationship of gap junctions and compaction in the preimplantation mouse embryo.” Development Suppl., 113-118.
Becker, D.L., Evans, W.H., Green C.R. and Warner, A.E. (1995) Functional analysis of amino acid sequences in connexin 43 involved in intercellular communication through gap junctions. J. Cell Sci. 108, 1455-1467.
Becker, D.L., Evans, W.H., Green C.R. and Warner, A.E. (1995) “Functional block of gap junctional communication using antipeptide antibodies: Molecular localization of the putative binding sites. Intercellular communication through gap junctions.” Ed. Y. Kanno. Progress in Cell Research, 4; 427-430.
Becker, D.L., Lin, J.S. and Green G.R. (1999) Pluronic gel as a means of antisense delivery. InAntisense techniques in the CNS. A practical approach. Eds. R. Leslie, A.J. Hunter and H.A. Robertson. pp. 149-157.
Becker, D.L., McGonnell, I., Makarenkova, H., Patel, K., Tickle, C., Lorimer, J., and Green, C.R. (1999) Roles for alpha1 connexin in morphogenesis of chick embryos using a novel antisense approach. Dev. Genetics. 24, 33-42.
Becker, David L., et al., “Connexin alpha1 and cell proliferation in the developing chick retina.” Experimental Neurology, vol. 156, No. 2, Apr. 1999 pp. 326-332.
Bennett MV, Zukin RS. Electrical coupling and neuronal synchronization in the Mammalian brain. Neuron. Feb. 19, 2004; 41(4):495-511.
Berkovitz, B.K.B. and Becker, D.L. (2003) The detailed morphology and distribution of gap junction protein associated with cells from the intra-articular disc of the rat temporomandibular joint. Conn. Tiss. Res. 44, 12-18.
Bioconjugate Techniques (Greg T. Hermanson, ed., Academic Press, 1996) Ch. 17 & 2.
Bittman, K. Becker, D.L., Cicirata, F. and Parnavelas, J.G. (2002) Connexin expression in homotypic and heterotypic cell coupling in the developing cerebral cortex. J. Compo Neurol 443, 201-212.
Blackburn JP, Connat JL, Severs NJ, Green CR. Connexin43 gap junction levels during development of the thoracic aorta are temporally correlated with elastic laminae deposition and increased blood pressure. Cell Biol Int. Feb. 1997;21(2):87-97. PMID: 9080656 [PubMed—indexed for MEDLINE.
Blackburn

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