Immunotoxin therapy of allergy

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530405, 530389, 530403, 530404, 530402, 530390, 424 88, 424 92, 424 91, 514885, 514829, 514389, C07K 1700, C07K 1500

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active

047147598

ABSTRACT:
A product and process for treating allergy are described. An immunotoxin specific for the IgE isotype is used to eliminate the IgE producing B-lymphocytes responsible for allergy.

REFERENCES:
patent: 4564600 (1986-01-01), Ali
patent: 4661347 (1987-04-01), Muller
Killen et al, J. Immunol., 133, 1984, pp. 2549-2553.
Jansen et al, Immunological Rev., 62, 1982, pp. 185-216.
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Farkas et al, Immunol., 45, 1982, pp. 483-492.
Masuho et al, J. Biochem, 91, 1982, pp. 1583-1591.
Ramakrishnon et al, Cancer Res., 44, 1984, pp. 201-208.

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