Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1994-12-30
1998-09-01
Fan, Jane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514622, 514617, 514619, 514532, 514534, 514616, 514618, 560 39, 560 41, 560 42, 564155, 564158, 564170, 564176, 564182, 564180, 564169, 564183, 564219, 564220, C07C22918, A01N 3746
Patent
active
058011951
ABSTRACT:
Novel aryl amides are inhibitors of tumor necrosis factor .alpha. and can be used to combat cachexia, endotoxic shock, and retrovirus replication. A typical embodiment is N-benzoyl-3-amino-3-(3',4'-dimethoxyphenyl)propanamide.
REFERENCES:
patent: 4440941 (1984-04-01), Shu et al.
patent: 5173496 (1992-12-01), Bruneau et al.
patent: 5298652 (1994-03-01), Carson et al.
F. Bachelerie et al. (Apr. 25, 1991) Nature, vol. 350, pp. 709-712.
Debajit K. Biswas et al. (1993) Journal of Acquired Immune Deficiency Syndromes, vol. 6, pp. 778-786.
Ghassan S. Dbaibo et al. (Aug. 25, 1993) The Journal of Biological Chemistry, vol. 265(24), pp. 17762-17766.
Elia J. Duh et al. (Aug. 1989) Proc. Natl. Acad. Sci. USA, vol. 86, pp. 5974-5978.
Alexander N. Shakhov et al. (Jan. 1990) J. Exp. Med., vol. 171, pp. 35-47.
Frank J. T. Staal et al. (Dec. 1990) Proc. Natl. Acad. Sci. USA, vol. 87, pp. 9943-9947.
Yuichiro J. Suzuki et al. (Dec. 30, 1992) Biochemical and Biophysical Research Communications, vol. 189(3), pp. 1709-1715.
Yuichiro J. Suzuki et al. (May 28, 1993) Biochemical and Biophysical Research Communications, vol. 193(1), pp. 277-283.
Yuichiro J. Suzuki et al. (Nov. 1993) Biochemistry and Molecular Biology International, vol. 31(4), pp. 693-700.
CA 78:97267, Giordano et al., 1973.
CA 206:49944, Barr et al., 1987.
Ca 88:190339, Borgna et al., 1978.
CA 112:118481, Imuda et al., 1990.
CA 122:265391 Itoh et al. 1995.
CA 122: 10049 Yamada et al. 1994.
CA 119:139266 Carceller et al. 1992.
CA 121: 204912 Davis et al. 1994.
CA 117: 169556 Buchardt et al. 1992.
CA 114: 117572 Reed et al. 1991.
CA 113: 6817 Komura et al. 1988.
CA 112: 42565 Shiokari et al. 1986.
Muller George W.
Shire Mary
Stirling David I.
Celgene Corporation
Fan Jane
LandOfFree
Immunotherapeutic aryl amides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunotherapeutic aryl amides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunotherapeutic aryl amides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-270674