Immunosuppressive method with dithiocarbamates

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A61K 3127

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active

041668669

ABSTRACT:
The present invention provides certain novel .omega.-(alkoxycarbonyl)alkyl esters of dithiocarbanilic acid and certain aryl-substituted acids related thereto. These compounds are disclosed as immunoregulatory agents, useful in the treatment of organ transplant reject phenomena and autoimmune diseases such as arthritis.
Additionally, there is described by the present invention the immunoregulatory use of .omega.-carboxyalkyl and .omega.-(alkoxycarbonyl)alkyl esters of dithiocarbanilic acid and certain aryl-substituted acids related thereto.

REFERENCES:
patent: 3686413 (1972-08-01), Hollrah
patent: 3876796 (1975-04-01), Fujinami et al.

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