Immunostimulating guanine derivatives, compositions and methods

Details Immunostimulating guanine derivatives, compositions and methods Immunostimulating guanine derivatives, compositions and methods

1988-05-05

1991-04-30

Rollins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

A61K 3170, C08B 3100

Patent

active

050118285

ABSTRACT:
7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are .dbd.O, .dbd.S, .dbd.Se and .dbd.NCN. Compositions and methods of use are also disclosed.

REFERENCES:
Chem. Abst. 72: 55806j, 1970.
Chem. Abst. 106: 16903q, 1987.

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