Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-12-19
1993-05-18
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514338, 546271, 548154, C07D51304, A61K 31425
Patent
active
052121925
ABSTRACT:
The present invention relates to novel 6-aryl-5,6-dihydroimidazo[2,1-b]thiazole derivatives having immunostimulating properties, which are useful for treating humans and warm-blooded animals suffering from disorders and/or diseases wherein the immune system is impaired or suppressed. Processes of preparing said novel compounds and compositions containing the same as active ingredient.
REFERENCES:
patent: 3274209 (1966-09-01), Raeymaekers et al.
patent: 4340738 (1982-07-01), Sipido
patent: 4584305 (1986-04-01), Brugmans
patent: 4910315 (1990-03-01), Yamamoto
Otterness et al., "Effect of Levamisole on the Mitosis of Murine Thymoctes in Culture", Immunopharmacology 1, 245-254 (1979).
Merluzzi et al., "In vitro stimulation of murine lymphoid cell cultures by levamisole", Clin. exp. Immunol., 22, 486-492 (1975).
Hammouda et al., CA; 101: 211027f (1984).
Robert et al., CA; 97: 55735b, and J. Heterocycl. Chem., 19, 343-348 (1982).
Brabander et al., "Levamisole and R 26390: in search for better insight and activity.", Acta Antwerpiensia, 1991, 8 (2), 37-46.
Van Wauwe et al., "Anti-CD3 stimulation of murine spleen cells: comitogenic effects of levamisole and R 26390", International Journal of Immunopharmacology, 1991, 13 (6), 764.
Raeymaekers Alfons H. M.
Roevens Leopold F. C.
Van Laerhoven Willy J. C.
Van Wauwe Jean P. F.
Gerstl Robert
Janssen Pharmaceutica N.V.
Metz Charles J.
LandOfFree
Immunostimulating 6-aryl-5,6-dihydroimidazo[2,1-b]thiazole deriv does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunostimulating 6-aryl-5,6-dihydroimidazo[2,1-b]thiazole deriv, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunostimulating 6-aryl-5,6-dihydroimidazo[2,1-b]thiazole deriv will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-804724