Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1991-11-05
1993-11-09
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
422 56, 435 793, 435970, 435975, 436501, 436514, 436518, 436541, 436810, G01N 33538, G01N 33543, G01N 33548
Patent
active
052601943
ABSTRACT:
A method and device for determining the presence of an analyte in a sample suspected of containing the analyte is disclosed. The method involves contacting a test solution containing the sample, an antibody for the analyte, and a conjugate of the analyte and a label with a contact portion of a piece of bibulous material capable of being traversed in at least one direction by the test solution through capillary action. The bibulous material contains a first receptor capable of binding to said conjugate. The first receptor is non-diffusively bound to a situs on the bibulous material separate from the contact portion. The bibulous material further contains a second receptor capable of binding the antibody to the analyte between the situs and the contact portion. The second receptor is non-diffusively bound to the bibulous material. At least a portion of the test solution is allowed to traverse the bibulous material by capillary action and thereby contact the situs. The situs is examined for the presence of the conjugate. To this end, the situs can be exposed to a signal producing means capable of interacting with the label to produce a signal in relation to the amount of analyte in the test solution. The signal produced at the situs is then detected.
REFERENCES:
patent: 4094647 (1978-06-01), Deutsch et al.
patent: 4258001 (1981-03-01), Pierce et al.
patent: 4366241 (1982-12-01), Tom et al.
patent: 4459358 (1984-07-01), Berke
patent: 4740468 (1988-04-01), Weng et al.
patent: 4806311 (1989-02-01), Greenquist
patent: 4861711 (1989-08-01), Friesen et al.
patent: 5085987 (1992-02-01), Olson
E. Uhlein, Rompps Chemical Dictionary, vol. 2, pp. 399-400 (translated to English).
Leitereg Theodore J.
Saunders David
Syntex (U.S.A.) Inc.
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