Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2006-09-07
2008-09-16
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
C514S646000, C564S123000, C564S244000
Reexamination Certificate
active
07425578
ABSTRACT:
Compounds are disclosed having the structure of Formula I:where R1, R3, and R4are independently hydrogen or C1to C4alkyl, and R2is:where R5is selected from the group consisting of hydrogen and C1to C4alkyl, orwhere R6, R7and R8are independently hydrogen or C1to C4alkyl; or the esters or pharmacologically acceptable salts thereof. Such compounds may be utilized for the prophylaxis or treatment of various diseases, particularly inflammatory conditions of the GI tract.Methods of treating inflammatory conditions of the GI tract such as inflammatory bowel disease using compounds having the following formula are also disclosed:where R9, R10and R11are independently selected from the group consisting of hydrogen and C1to C4alkyl, and R12is selected from the group consisting of hydrogen and —C(O)R13, where R13is a C1to C6alkyl or an aryl group.
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pate
Ekwuribe Nnochiri N.
Riggs-Sauthier Jennifer
Biocon Limited
Coppins Janet L.
Fuierer Marianne
Moore & Van Allen PLLC
Saeed Kamal A.
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