Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Patent
1995-05-12
1997-09-23
Woodward, Michael P.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
4242281, 530350, 435 5, A61K 3929, C12Q 170, C07K 1418
Patent
active
056701535
ABSTRACT:
This invention relates generally to immunoreactive polypeptide compositions comprising hepatitis type C viral epitopes, methods of using the compositions in immunological applications, and materials and methods for making the compositions.
REFERENCES:
patent: 5350671 (1994-09-01), Houghton et al.
patent: 5372928 (1994-12-01), Miyamura et al.
Farci et al., "Lack of Protective Immunity . . . ," Science 258:135-140 (1992).
Hijikata et al., "Hypervariable Regions . . . ", Biochem. Biophys. Res Comm 175:220-228 (1991).
Takeuchi et al., "The Putative Nucleocapsid and Envelope Protein . . . ", J Gen Virol. 71:3027-3033 (1990).
Kubo et al., 1989, Japan Nucl. Acids Res 17(24):10367-10372.
Choo et al. 1990, Brit. Med. Bull. 46:423-442.
Kato et al., 1990, Proc. Natl. Acad. Sci. USA 87:9524-9528.
Takeuchi et al., 1990, Gene 91:287-291.
Takeuchi et al., 1990, J. Gen. Virol. 71:3027-3033.
Takeuchi et al., 1990, Nucl. Acids Res. 18(15):4626.
Choo et al., 1991, Proc. Natl. Acad. Sci. USA 88:2451-2455.
Han et al., 1991, Proc. Natl. Acad. Sci. USA 88:2451-2455.
Okamoto et al., 1991, Japan J. Exp. Med. 60(3):167-177.
Takamizawa et al., 1991, J. Virol. 65:1105-1113.
Weiner et al., 1991, Virol. 180:842-848.
Houghton et al., 1991, Hepatology 14(2):381-388.
Goodenow, M., et al., "HIV-1 isolates are rapidly evolving quasispecies: Evidence for viral mixtures and preferred nucleotide substitutions" Journal of Acquired Immune Defficiency Syndromes (1989) 2(4):344-352.
Weiner et al., "Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections" Proc. Natl. Acad. Sci. USA (1992) 89:3468-3472.
Okamoto et al., "Nucleotide sequence of the genomic RNA of hepatitis C virus isolated from a human carrier: comparison with reported isolates for conserved and divergent regions" Journal of General Virology (1991) 72(11):2697-2704.
Kremsdorf et al., "Partial nucleotide sequence analysis of a French hepatitis C virus: implications for HCV genetic variability in the E2/NS1 protein" Journal of General Virology (1991) 72:2557-2561.
Houghton Michael
Weiner Amy J.
Blackburn Robert P.
Chiron Corporation
Harbin Alisa A.
Wolffe Susan A.
Woodward Michael P.
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