Immunoradiometric assay employing terminal radionuclide labeling

Details Immunoradiometric assay employing terminal radionuclide labeling Immunoradiometric assay employing terminal radionuclide labeling

1979-06-29

1982-03-16

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 424 12, G01N 3348, G01N 3356, A61K 4300

Patent

active

043201091

ABSTRACT:
An immunoradiometric assay in which an antigen is reacted to its specific antibody, which complex is then separated and further reacted with a second, universal antibody. This second, universal antibody contains a chelating moiety, such as transferrin, capable of binding specifically and strongly short-lived radionuclides. The second complex, once formed is reacted with a radionuclide and the radio-activity is measured, determining thereby the quantity of the unknown antigen originally present.

REFERENCES:
patent: 4034074 (1977-07-01), Miles
patent: 4041146 (1977-08-01), Giaever
patent: 4166844 (1979-09-01), Tu

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